Benazepril Hydrochloride, Lisinopril, Ramipril, or Losartan Potassium in Treating Hypertension in Patients With Solid Tumors
NCT01234922 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 6
Last updated 2018-08-28
Summary
RATIONALE: Benazepril hydrochloride, lisinopril, ramipril, and losartan potassium may help lower blood pressure.
PURPOSE: This phase II trial is studying how well benazepril hydrochloride, lisinopril, ramipril, or losartan potassium works in treating hypertension in patients with solid tumors.
Conditions
- Hypertension
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- DRUG
-
lisinopril
Given orally
- DRUG
-
losartan potassium
Given orally
- OTHER
-
laboratory biomarker analysis
Correlative studies
- DRUG
-
benazepril hydrochloride
Given orally
- DRUG
-
ramipril
Given orally
Sponsors & Collaborators
-
Wake Forest University Health Sciences
lead OTHER
Principal Investigators
-
William Petty · Wake Forest University Health Sciences
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-02-28
- Primary Completion
- 2013-12-31
- Completion
- 2014-04-30
- FDA Drug
- Yes
Countries
- United States
Study Locations
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