A Study of Safety and Efficacy in MK-0954A Combination in Participants With Hypertension (MK-0954A-373 AM3)
NCT01431508 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2024-05-22
Summary
This study is being conducted to evaluate the safety and antihypertensive efficacy of MK-0954A (Losartan 50 mg / Hydrochlorothiazide (HCTZ) 12.5 mg) in participants with mild to moderate essential hypertension.
Conditions
Interventions
- DRUG
-
Losartan 50 mg / HCTZ 12.5 mg
Losartan 50 mg / HCTZ 12.5 mg tablet once daily for 12 weeks
Sponsors & Collaborators
-
Organon and Co
lead INDUSTRY
Principal Investigators
-
Du-Yi Lee, M.D. · Cheng Ching General Hospital
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-08-01
- Primary Completion
- 2009-06-01
- Completion
- 2009-06-01
More Related Trials
-
Study of Losartan in Pediatric Patients With Hypertension (MK-0954-337)
NCT00756938 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Losartan Compared to Losartan/HCTZ in Pediatric Patients With Hypertension (0954A-327)
NCT00447603 ·Status: TERMINATED ·Phase: PHASE3
-
Bioequivalence of Losartan and Hydrochlorothiazide (HCTZ) Combination Tablet and Coadministration of Its Components (0954A-306)
NCT00953680 ·Status: COMPLETED ·Phase: PHASE1
-
Obese Hypertension Study (0954-315)
NCT00289887 ·Status: COMPLETED ·Phase: PHASE3
-
Hydrochlorothiazide (+) Losartan Potassium vs. Amlodipine Comparative Study (0954A-314)
NCT00157963 ·Status: COMPLETED ·Phase: PHASE4
-
Losartan and HCTZ and Amlodipine vs Atenolol and Amlodipine (0954A-309)(COMPLETED)
NCT00140959 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Investigate the Antihypertensive Efficacy of MK0954
NCT00887250 ·Status: COMPLETED ·Phase: PHASE3
-
Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy for Patients With Moderate Hypertension
NCT00095550 ·Status: COMPLETED ·Phase: PHASE3
-
Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy as First Line Treatment for Severe Hypertension
NCT00095394 ·Status: COMPLETED ·Phase: PHASE3
-
Antihypertensive Efficacy and Safety of Approved Drugs in Japanese Patients With Essential Hypertension (Banyu Study)(0954A-302)
NCT00092209 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate the Efficacy and Safety of Combined Administration of TAK-536CCB and Hydrochlorothiazide in Patients With Grade I or II Essential Hypertension.
NCT02072330 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
The Efficacy and Safety Study of Anti-hypertension Combination Drug in Patients Uncontrolled With Monotherapy.
NCT01828359 ·Status: COMPLETED ·Phase: PHASE4
-
The Effect of Losartan and Losartan Plus Isosorbide Mononitrate on Central Blood Pressure Measurements (0954-317)
NCT00943852 ·Status: COMPLETED ·Phase: PHASE1
-
MK0954 Versus Placebo for Treatment of Mild to Moderate Hypertension
NCT00888355 ·Status: COMPLETED ·Phase: PHASE3
-
Antiproteinuric Efficacy of Losartan Potassium in Patients With Non-Diabetic Proteinuric Renal Diseases (0954-213)
NCT00140985 ·Status: COMPLETED ·Phase: PHASE4
-
Olmesartan Comparison to Losartan in Hypertensive Subjects
NCT00949884 ·Status: COMPLETED ·Phase: PHASE4
-
A Long-term Study of the Safety of MK-0954A in Patients With Essential Hypertension (MK-0954A-351)
NCT01307033 ·Status: COMPLETED ·Phase: PHASE3
-
ACTUAL: Efficacy and Safety of Irbesartan/Hydrochlorothiazide Combination
NCT00708344 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Losartan/Chlorthalidone vs Losartan/Hydrochlorothiazide in Essential Arterial Hypertension
NCT04927299 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase 2 Study to Assess Dose-response Relationship of HCP1803 in Patients With Essential Hypertension
NCT03897868 ·Status: COMPLETED ·Phase: PHASE2
-
An Observational Study to Investigate the Efficacy, Safety, Tolerability and the Effect on Quality of Life of Telmisartan (Micardis) and Telmisartan With HCTZ (Micardis Plus) in Patients With Hypertension
NCT00904215 ·Status: COMPLETED
-
Efficacy of Losartan + Amlodipine Compared to Amlodipine Alone in the Treatment of Uncontrolled High Blood Pressure (MK-0954F-399)
NCT01277822 ·Status: COMPLETED ·Phase: PHASE4
-
Pharmacokinetic Interactions of Losartan and Hydrochlorothiazide
NCT01858623 ·Status: COMPLETED ·Phase: NA
-
PROBE Parallel 6-week Treatment Comparing Telmisartan/Hydrochlorothiazide (HCT) (40/12.5 or 80/12.5) With Losartan/HCT (50/12.5) Using Ambulatory Blood Pressure Monitoring (ABPM)
NCT00274638 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Evaluate the Trough and Peak Effect of Once Daily Telmisartan 80 mg/Hydrochlorothiazide 12.5 mg (Micardis Plus) by Ambulatory Blood Pressure Monitoring (ABPM) in Patients With Mild to Moderate Essential Hypertension
NCT00257491 ·Status: COMPLETED ·Phase: PHASE3