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Comparison of Effects Between Amlodipine and Hydrochlorothiazide in Combination With Losartan on 24-hr Central Blood Pressure in Hypertensive Patients

NCT02294539 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 231

Last updated 2017-03-15

No results posted yet for this study

Summary

The purpose of this study is to investigate which combination therapy is more effective for improving the blood pressure (BP) and AM central SBP in hypertensive patients:Angiotensin II receptor blocker (ARB) plus calcium channel blocker (CCB) or ARB plus diuretics

Conditions

Interventions

DRUG

Losartan 50mg/amlodipine 5mg

once daily, 1T, PO medication

DRUG

Losartan 100mg/amlodipine 5mg

once daily, 1T, PO medication

DRUG

Losartan 50mg/Hydrochlorothiazide 12.5mg

once daily, 1T, PO medication

DRUG

Losartan 100mg/Hydrochlorothiazide 25mg

once daily, 1T, PO medication

Sponsors & Collaborators

  • Hanmi Pharmaceutical Company Limited

    collaborator INDUSTRY

  • Chong-Jin Kim

    lead OTHER

Principal Investigators

  • Chong-Jin Kim · Kyung Hee University Hospital at Gangdong

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
19 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-08-31
Primary Completion
2016-05-18
Completion
2016-05-18

Countries

  • South Korea

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02294539 on ClinicalTrials.gov