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Impact of Neurally Adjusted Ventilator Assist (NAVA) Mode on Patient Ventilator Asynchrony Using Helmet

NCT01161875 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2011-08-05

No results posted yet for this study

Summary

Non invasive ventilation has been proposed to reduce the incidence of ventilatory dysfunction following abdominal aortic surgery. However, the nasogastric tube reduces the airtightness of the facial mask used to perform non invasive ventilation and induces air leaks. The use of a helmet reduces air leaks, thus seems adequate to ensure patient-ventilator interface. However, the high dead space related to helmet volume is responsible for asynchrony between patient demand and ventilatory support delivery. The investigators hypothesized driving the ventilator based on a neural signal (diaphragm electrical activity) would reduce patient-ventilator asynchronies.

Conditions

  • Non-Invasive Positive-Pressure Ventilation

Interventions

DEVICE

Neurally Adjusted Ventilatory Assistance

In ICU following abdominal aortic surgery, in extubated patient, non-invasive ventilation was performed as follows: * facial mask with non-invasive pressure support ventilation mode to define settings for helmet ventilation * helmet use with non-invasive pressure support ventilation mode to define adequate settings * helmet use with neurally adjusted ventilatory assist mode, based on previous settings

Sponsors & Collaborators

  • Pierre and Marie Curie University

    lead OTHER

Principal Investigators

  • Thomas Similowski, MD, PhD · Groupe Hospitalier Pitie-Salpetriere

  • Mathieu RAUX, MD, PhD · Groupe Hospitalier Pitie-Salpetriere

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-11-30
Primary Completion
2010-12-31
Completion
2010-12-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01161875 on ClinicalTrials.gov