Postprandial Inflammation and Fatty Acids
NCT00977262 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 42
Last updated 2010-04-21
Summary
The main objective is to elucidate the acute effects of an oral intake of either saturated, monounsaturated or polyunsaturated fatty acids on peripheral blood mononuclear cells (PBMC) whole genome expression of obese and type 2 diabetic obese subjects.
Conditions
- Cardiovascular Disease
- Diabetes Type 2
- Obesity
Interventions
- OTHER
-
High saturated fat shake
milkshake containing 95 gram of fat, high percentage of saturated fat
- OTHER
-
High monounsaturated fat shake
milkshake containing 95 gram of fat, high percentage of monounsaturated fat
- OTHER
-
High polyunsaturated fat shake
milkshake containing 95 gram of fat, high percentage polyunsaturated fat
Sponsors & Collaborators
-
Dutch Diabetes Research Foundation
collaborator OTHER -
Wageningen University
lead OTHER
Principal Investigators
-
Michael Muller, Prof · Chair Department of Human Nutrition NMG group
-
Lydia A Afman, PhD · Senior scientist department Human Nutrition Wageningen University
Study Design
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 50 Years
- Max Age
- 70 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-10-31
- Primary Completion
- 2009-12-31
- Completion
- 2009-12-31
Countries
- Netherlands
Study Locations
More Related Trials
-
Postprandial Dysmetabolism
NCT00813215 ·Status: UNKNOWN ·Phase: NA
-
FFA Hypertension and Inflammation in Lean and Obese Subjects
NCT00721617 ·Status: COMPLETED ·Phase: NA
-
Lipid, Glycemic, and Insulin Responses to Meals Rich in Different Fatty Acids
NCT00479791 ·Status: COMPLETED ·Phase: NA
-
Complex Effects of Dietary Manipulation on Metabolic Function, Inflammation and Health
NCT02706262 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Role of Dietary Fatty Acids in Fatty Liver and Insulin Resistance
NCT01038102 ·Status: COMPLETED ·Phase: NA
-
Search for Biological Markers of Orosensory Perception of Fatty Acids in Healthy Subjects and Possible Modifications in Patients With Type 2 Diabetes and in Obese Non-diabetic Patients.
NCT02028975 ·Status: COMPLETED ·Phase: NA
-
Effects of 10-gram Collagen Protein Hydrolysate on Cardiometabolic Health
NCT05282641 ·Status: COMPLETED ·Phase: NA
-
Rectal Short Chain Fatty Acids Combinations and Substrate and Energy Metabolism
NCT01983046 ·Status: COMPLETED ·Phase: NA
-
Acute Glycemic Effects of a Very Low Fat Diet in Type 2 Diabetes
NCT00006432 ·Status: COMPLETED ·Phase: NA
-
Pilot Study to Test Dietary Fat Delivery
NCT02101996 ·Status: COMPLETED
-
Dietary Lipids, Energy Expenditure and Obesity Biomarkers
NCT02656940 ·Status: COMPLETED ·Phase: NA
-
Effect of an Antiinflammatory Diet on Postprandial Gene Expression of Mononuclear Cells of Adult Obese Women
NCT04920409 ·Status: COMPLETED ·Phase: NA
-
Dietary Interventions in Prediabetes
NCT01729078 ·Status: COMPLETED ·Phase: NA
-
Acute Effects of Oral Carbohydrate and Fat Loads on Systemic Microvascular Endothelial Function in Healthy Individuals.
NCT03515460 ·Status: COMPLETED ·Phase: NA
-
B195: Effect of Diet-Induced Energy Deficit and Body Fat Reduction on Inflammatory Markers in Obese Subjects
NCT00302926 ·Status: COMPLETED ·Phase: NA
-
Comparative Analysis of Postprandial Effects in Healthy and Obese Individuals
NCT06645756 ·Status: COMPLETED ·Phase: NA
-
Effects of Low and Moderate Fat Diets on Lipids, Inflammation and Vascular Reactivity in the Metabolic Syndrome
NCT00362908 ·Status: COMPLETED ·Phase: NA
-
Overfeeding Induced Fat-tissue Stimulation
NCT06193668 ·Status: RECRUITING ·Phase: NA
-
Lipids and Insulin Sensitivity
NCT01466816 ·Status: COMPLETED ·Phase: NA
-
Exploring the Molecular Basis to Healthy Obesity: The Diabetes Risk Assessment Study
NCT01884714 ·Status: COMPLETED ·Phase: NA
-
Free Fatty Acids-Induced Hypertension in Obese Subjects (Aim #2)
NCT02406586 ·Status: COMPLETED ·Phase: NA
-
The Fasting Study - Unraveling the Mechanistic Effects of Prolonged Fasting in Humans.
NCT03757767 ·Status: COMPLETED ·Phase: NA
-
Glucose and Insulin Responses to Test Foods
NCT01671878 ·Status: COMPLETED ·Phase: NA
-
Effect of Reduction of Inflammatory Status on Glucose Metabolism in Overweight Men
NCT00221052 ·Status: COMPLETED ·Phase: NA
-
Triglyceride Rich Lipoproteins and Platelet Activation in Type 2 Diabetes
NCT03561571 ·Status: COMPLETED ·Phase: NA