Pilot Study to Test Dietary Fat Delivery
NCT02101996 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 9
Last updated 2016-08-19
Summary
The average American diet consumed by a significant proportion of the adult population, supplies excessive calories and large amounts of saturated fat. Saturated fats can be cleared and used in skeletal muscle, but in obese individuals, biomarkers of saturated fat are found in the blood, along with markers of poor muscle metabolism.
Both fats and amino acids are processed by the same metabolic pathways in muscle, and the investigators hypothesize that meals with greater amounts of saturated fat slow muscle metabolism. A better understanding of the interaction of these to metabolites will allow for the development of future medications to treat muscle loss in sick individuals and the elderly.
Conditions
Interventions
- OTHER
-
high-fat diet
Subjects consume a high-fat diet for three weeks before the in-hospital stay.
Sponsors & Collaborators
-
University of Missouri-Columbia
lead OTHER
Principal Investigators
-
Elizabeth J Parks, PhD · Univ of Missouri-Columbia
Eligibility
- Min Age
- 30 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-06-30
- Primary Completion
- 2016-03-31
- Completion
- 2016-08-31
Countries
- United States
Study Locations
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