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Energy Metabolism and Cognitive Aging

NCT00777010 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 62

Last updated 2017-03-24

No results posted yet for this study

Summary

Participants 60 and older with and without Parkinson's disease who have mild cognitive decline will be randomized to either a standard higher carbohydrate diet or a carbohydrate-restricted ketogenic diet for 8 weeks. The main hypothesis is that nutritional ketosis will improve memory functioning. Pre and post-memory testing will be performed. Subjects will also provide blood samples and a subset of subjects with receive magnetic resonance brain imaging.

Conditions

Interventions

OTHER

Ketogenic diet

carbohydrate restricted diet

OTHER

Healthy high carbohydrate diet

higher carbohydrate diet

Sponsors & Collaborators

  • University of Cincinnati

    lead OTHER

Principal Investigators

  • Robert Krikorian, PhD · University of Cincinnati

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-09-01
Primary Completion
2016-12-31
Completion
2017-03-15

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00777010 on ClinicalTrials.gov