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Investigating the Production of Lipoproteins and Acetyl-CoA During a Ketogenic Diet

NCT03901014 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 4

Last updated 2026-05-18

No results posted yet for this study

Summary

The purpose of this study is to understand how the reduction in dietary carbohydrates in a very-low carbohydrate ketogenic diet impacts the synthesis of cholesterol, fatty acid, and ketones, and the turnover rate of VLDL and chylomicron particles.

Conditions

  • Cholesterol Metabolism
  • Ketone Metabolism

Interventions

OTHER

Standard American diet

Standard American diet with 50% energy from carbohydrate, 30% from fat, and 20% from protein.

OTHER

Very low carbohydrate diet

Ketogenic diet with \<50g carbohydrate, 60-75% energy from fat, and 20% from protein

Sponsors & Collaborators

  • Touro University, California

    lead OTHER

Principal Investigators

  • Grace M Jones, PhD · Touro University, California

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-29
Primary Completion
2019-04-18
Completion
2019-04-18

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03901014 on ClinicalTrials.gov