Airway Epithelium Gene Expression: AEGIS IDE

Summary

The purpose of the research study is to develop a new, more sensitive, and less invasive test for diagnosing lung cancer at an earlier stage, when it can more easily be cured. The investigators hypothesize that certain genes are expressed differently in current and former smokers who have lung cancer, and this difference in gene expression may be a biomarker for lung cancer.

Conditions

• Lung Cancer

Interventions

DEVICE

Biomarker (not used as an intervention)

This study is an observational study. There is no intervention.

Sponsors & Collaborators

• University of Pennsylvania

  collaborator OTHER

• Columbia University

  collaborator OTHER

• Temple University

  collaborator OTHER

• Indiana University

  collaborator OTHER

• University of Alabama at Birmingham

  collaborator OTHER

• University of Missouri-Columbia

  collaborator OTHER

• Louisiana State University Health Sciences Center in New Orleans

  collaborator OTHER

• University of Wisconsin, Madison

  collaborator OTHER

• Medical University of South Carolina

  collaborator OTHER

• National Jewish Health

  collaborator OTHER

• Overlake Hospital Bellevue WA

  collaborator UNKNOWN

• Pulmonary and Allergy Associates of New Jersey

  collaborator UNKNOWN

• Pulmonary Associates of Arizona

  collaborator UNKNOWN

• William Jennings Bryan Dorn VA Medical Center

  collaborator FED

• Virginia Commonwealth University

  collaborator OTHER

• Jamaica Hospital Medical Center

  collaborator OTHER

• North Florida/South Georgia Veterans Health System

  collaborator OTHER

• Steward St. Elizabeth's Medical Center of Boston, Inc.

  collaborator OTHER

• University of California, Davis

  collaborator OTHER

• Yale University

  collaborator OTHER

• The Cleveland Clinic

  collaborator OTHER

• Allegro Diagnostics, Corp.

  lead INDUSTRY

Principal Investigators

• Duncan Whitney, PhD · Allegro Diagnostics

Eligibility

Min Age

21 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2010-02-28

Primary Completion

2014-12-31

Completion

2015-02-28

Countries

• United States

Study Locations