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Incorporation of Genetic Expression of Airway Epithelium With CT Screening for Lung Cancer

NCT01982149 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 27

Last updated 2020-07-24

No results posted yet for this study

Summary

Lung cancer, largely the result of cigarette smoking, is the leading cause of cancer death in the United States, killing over 160,000 people in 2010, more than breast, colorectal, and prostate cancer combined. Since only 10% of heavy smokers develop lung cancer and 20% of lung cancers develop in nonsmokers, it is thought that genetic predisposition plays an important role. This study proposes to examine the genetic correlation between nasal and bronchial epithelium and to identify a patient's risk for lung cancer earlier.

Conditions

Interventions

GENETIC

Group 1

Perform gene expression studies of airway epithelium to correlate findings in the gene expression of nasal bronchial epithelium

GENETIC

Group 2

Correlate gene expression data from nasal and bronchial epithelium

GENETIC

Group 3

Correlated nasal epithelial gene expression with the ultimate diagnosis (by biopsy or surgery)

Sponsors & Collaborators

  • Weill Medical College of Cornell University

    lead OTHER

Principal Investigators

  • Ronald G Crystal, MD · Weill Medical College of Cornell University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-06-30
Primary Completion
2019-05-31
Completion
2019-05-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01982149 on ClinicalTrials.gov