Detection of Either the EML4-ALK Gene Rearrangements or the T790M EGFR Mutation in the Plasma of Advanced NSCLC Patients
NCT03236675 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2021-09-30
Summary
Demonstrate feasibility of detection of EML4-ALK fusion transcripts and T790M EGFR mutation from exosomes in the circulation of Non-Small Cell Lung Cancer (NSCLS) patients.
Conditions
- Carcinoma, Non-Small-Cell Lung
Sponsors & Collaborators
-
Exosome Diagnostics, Inc.
lead INDUSTRY
Principal Investigators
-
Roger Tun · Exosome Diagnostics, Inc.
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-03-31
- Primary Completion
- 2022-02-28
- Completion
- 2022-02-28
Countries
- United States
Study Locations
More Related Trials
-
Improving the Early Detection of Lung Cancer by Combining Exosomal Analysis of Hypoxia With Standard of Care Imaging
NCT04629079 ·Status: UNKNOWN
-
Pronostic and Predictive Value of EMT in Localized Lung Cancer
NCT03509779 ·Status: RECRUITING
-
Prediction of Immunotherapeutic Effect of Advanced Non-small Cell Lung Cancer
NCT04427475 ·Status: UNKNOWN ·Phase: NA
-
Identifying Early Lung Cancer Cells in Malignant Pleural Effusion Samples From Patients With Primary Lung Cancer
NCT00897143 ·Status: WITHDRAWN
-
Research of the EML4-ALK Gene Expression in the Pleural Effusion or Tumor Tissue From Lung Cancer Patients
NCT01257308 ·Status: UNKNOWN
-
Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy
NCT03042221 ·Status: RECRUITING
-
Molecular Profiling and Dynamic Changes of ctDNA in Unresectable Locally Advanced NSCLC
NCT05641870 ·Status: UNKNOWN
-
Construction of Microfluidic Exosome Chip for Diagnosis of Lung Metastasis of Osteosarcoma
NCT05101655 ·Status: COMPLETED
-
Proteomics in Small Cell Lung Cancer
NCT05623956 ·Status: RECRUITING
-
Construction and Use of Lung Tumor Microarray for the Analysis of Gene Expression in Lung Cancer
NCT00340847 ·Status: COMPLETED
-
Serum Exosomal Long Noncoding RNAs as Potential Biomarkers for Lung Cancer Diagnosis
NCT03830619 ·Status: COMPLETED
-
Immune Checkpoint Inhibitors in Advanced Non-small Cell Lung Cancer and Discovery of New Biomarkers
NCT03658460 ·Status: COMPLETED
-
Molecular Landscape Analysis and Clinical Implications for NSCLC Patients With Rare Mutations
NCT05701787 ·Status: RECRUITING
-
Clinicopathological Features of NSCLC Patients Associated With the Chromosome 2p (EML4-ALK)
NCT01662635 ·Status: COMPLETED
-
PROSPECT - Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target Identification
NCT05049837 ·Status: RECRUITING
-
Lung Cancer Next Generation Sequencing Using the Oncomine Comprehensive Assay
NCT03558165 ·Status: COMPLETED
-
The Utility of Circulating Tumor Cells as Confirmation of Pathologic Diagnosis in Patients With Suspected Early Stage Non-small Cell Lung Cancer
NCT02380196 ·Status: COMPLETED
-
Analysis of Circulating Tumor DNA Dynamics to Predict and Monitor Response to TKI in Patients With Advanced NSCLC.
NCT06167460 ·Status: RECRUITING
-
Development and Application of Molecular Evaluation Instrument for Lung Cancer Diagnosis and Treatment
NCT06086587 ·Status: NOT_YET_RECRUITING
-
Correlation Between EGFR Mutation Using cfDNAs and Circulating Tumor Cells in Patients With NSCLC
NCT02422628 ·Status: UNKNOWN
-
Methylation Level of SHOX2 in Endobronchial Ultrasound With Real-time Guided Transbronchial Needle Aspiration for Lung Cancer Staging
NCT01653002 ·Status: COMPLETED
-
CirculAting Tumor DNA in Patients DIagnosed With Lung Metastasis From Colorectal Cancer: candiDate Selection for Local AblaTive thErapy
NCT04704960 ·Status: UNKNOWN
-
Multicenter Clinical Research for Early Diagnosis of Lung Cancer Using Blood Plasma Derived Exosome
NCT04529915 ·Status: UNKNOWN
-
Validation of Molecular Diagnostic Thecnologies for Lung Cancer Patients.
NCT03220230 ·Status: COMPLETED
-
Studying Tumor Tissue Samples From Patients With Early-Stage Non-Small Cell Lung Cancer
NCT01517971 ·Status: COMPLETED