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Detection of Genetic Markers of Lung Cancer

NCT00280202 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 6000

Last updated 2025-10-24

No results posted yet for this study

Summary

The purpose of this research study is to determine the genetic changes and immunologic changes that are involved in the development and progression of bronchogenic lung cancer.

Conditions

Interventions

PROCEDURE

Biopsy of the major carinal area

Biopsy performed intraoperatively

PROCEDURE

Biopsy of abnormal & suspicious areas of the bronchial tree

Biopsy performed intraoperatively

PROCEDURE

Evaluation of the tumor for DNA mutations

Tumor tissue is banked for future analysis.

PROCEDURE

Bronchoalveolar Lavage (BAL) for cytokine analysis

BAL performed intraoperatively

PROCEDURE

Correlation of flow cytometric & RT PCR for TNM stage

Tissues banked for future correlative studies

PROCEDURE

Analysis of lymph nodes

Tissues banked for future analysis

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • University of Pittsburgh

    lead OTHER

Principal Investigators

  • Arjun Pennathur, MD · Professor (with tenure) of Cardiothoracic Surgery

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1996-06-30
Primary Completion
2050-12-31
Completion
2050-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00280202 on ClinicalTrials.gov