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Calcium Retention as Influenced by Dietary Components That Induce an Acid Load

NCT00620763 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2018-07-02

Study results available
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Summary

The impact of protein sources such as beef as part of Western diet on calcium retention remains controversial. We propose to test the hypothesis that the positive effect of high protein intake (especially from meat protein) can offset the negative effect of protein-induced net acid load on bone metabolism and the retention of body calcium. Healthy postmenopausal women recruited from the community will consume two diets differing in meat protein and acid load for 7 weeks. Calcium retention from diets will be determined using a highly sensitive measurement of whole body retention of a calcium isotope added to the diet.

Conditions

  • Healthy

Interventions

OTHER

High Meat - High Potential Renal Acid Load (PRAL) diet

Menu high in meat protein

OTHER

Low Protein - Low Potential Renal Acid Load (PRAL) diet

Menu low in meat protein

Sponsors & Collaborators

  • USDA Grand Forks Human Nutrition Research Center

    lead FED

Principal Investigators

  • Jay Cao, PhD · USDA Grand Forks Human Nutrition Research Center

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
40 Years
Max Age
75 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-01-31
Primary Completion
2008-05-31
Completion
2008-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00620763 on ClinicalTrials.gov