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Effect of Ezetimibe Plus Simvastatin Versus Simvastatin Alone on Atherosclerosis in the Carotid Artery (ENHANCE)(P02578)

NCT00552097 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 720

Last updated 2024-08-15

No results posted yet for this study

Summary

The purpose of the study is to determine whether ezetimibe plus simvastatin will be more effective than simvastatin alone in preventing progression of atherosclerosis of the inner layer of the carotid artery.

Conditions

Interventions

DRUG

ezetimibe (plus simvastatin)

oral tablets; ezetimibe 10 mg (plus simvastatin 80 mg) once daily for 24 months

DRUG

placebo (plus simvastatin)

tablets; placebo to match ezetimibe 10 mg (plus simvastatin 80 mg) once daily for 24 months

Sponsors & Collaborators

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-06-01
Primary Completion
2006-04-25
Completion
2006-04-25

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00552097 on ClinicalTrials.gov