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Effect of Ezetimibe on Flow-mediated Brachial Artery Reactivity in Healthy Subjects

NCT00376246 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2020-02-12

Study results available
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Summary

The objective of this study is to show that Ezetimibe will improve endothelial function following high cholesterol meals in healthy subjects by decreasing absorption of cholesterol and thus affecting concentration and composition of remnant-like particles.

Conditions

  • Endothelial Dysfunction

Interventions

DRUG

Ezetimibe

Sponsors & Collaborators

Principal Investigators

  • Ori Ben-Yehuda, MD · UCSD

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-09-30
Primary Completion
2008-04-30
Completion
2008-04-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00376246 on ClinicalTrials.gov