MedTrace Logo

The Acute Effect of Statins on Inflammatory Markers of Athersclerotic Tissue

NCT00587717 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 35

Last updated 2023-12-12

No results posted yet for this study

Summary

This study is being done to determine if the acute administration of the drug Simvastatin reduces plaque tissue inflammation and plaque instability in patients undergoing carotid endarectomy

Conditions

  • Carotid Artery Disease

Interventions

DRUG

simvastatin

Two 80 mg pills simvastatin taken 24 hours prior to surgery

DRUG

placebo

take 2 80 mg pills placebo 24 hours prior to surgery

Sponsors & Collaborators

Principal Investigators

  • Amir Lerman, MD · Mayo Clinic

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-09-30
Primary Completion
2006-03-31
Completion
2006-03-31

More Related Trials

Entities

Drugs
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00587717 on ClinicalTrials.gov