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Single-Breath Measurement Underestimates Ventilatory Volume According to Emphysema Severity

NCT00528944 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 73

Last updated 2015-07-07

No results posted yet for this study

Summary

Although single breath helium (He) dilution measurement (VASB) is currently used in pulmonary function laboratories to assess functional alveolar volume and diffusing capacity for carbon monoxide, the extent to which VASB reflects ventilatory and thoracic volume has not been prospectively determined in emphysema. We hypothesized that VASB underestimates rebreathe helium dilution volume (VARB), and plethysmographic volume (VApleth) as clinical and physiologic severity of emphysema increases.

Conditions

  • Emphysema

Sponsors & Collaborators

Principal Investigators

  • Robert C Basner, MD · Columbia University

Eligibility

Min Age
18 Years
Max Age
81 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-01-31
Primary Completion
2008-07-31
Completion
2008-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00528944 on ClinicalTrials.gov