Study of the Physiology of the Asthma of the Obese Subjects. Breathing Obesity Asthma Study (BOA)
NCT00577733 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 204
Last updated 2013-09-18
Summary
Asthma is more frequent in obese women, but the mechanisms underlying the causes of this increased frequency are unknown and are different from usual asthma pathophysiology (associated with allergy). Obesity is known to influence ventilation; our hypothesis is that the normal variability of ventilation is decreased in obese patients, and that this decrease is responsible for an increased reactivity of their airway to non specific stimuli. In this observational study, breathing variability will be studied using polygraphy (an investigation that is made in these women to detect nocturnal apneas), and airway reactivity is studied between pulmonary function tests that are made before bariatric surgery.
Conditions
Sponsors & Collaborators
-
Assistance Publique - Hôpitaux de Paris
lead OTHER
Principal Investigators
-
DELCLAUX MD Christophe, PhD · Department of Physiology, Hôpital Européen Georges Pompidou
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2008-01-31
- Primary Completion
- 2010-06-30
- Completion
- 2010-11-30
Countries
- France
Study Locations
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