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Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Severe Asthma

NCT06985225 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 5

Last updated 2026-04-29

No results posted yet for this study

Summary

In this study, xenon MRI will be used to evaluate regional functional consequences of mucus plugs in the lungs of patients with severe asthma. Mucus plugs will be identified using CT imaging, and xenon MRI will be used to evaluate ventilation and gas exchange impairments in regions of the lungs corresponding to the airways downstream of mucus plugs.

Conditions

Interventions

COMBINATION_PRODUCT

Hyperpolarized 129 Xenon

Xenon gas contrast agent for MRI

Sponsors & Collaborators

  • Polarean Imaging, Plc

    collaborator UNKNOWN

  • University of Kansas Medical Center

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-01
Primary Completion
2026-12-31
Completion
2026-12-31
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06985225 on ClinicalTrials.gov