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Multiple Breath Washout, a Clinimetric Dataset

NCT03320382 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 530

Last updated 2022-05-06

No results posted yet for this study

Summary

Monitoring patients with chronic, inflammatory airways disease particularly in the early stages is hampered by the relative insensitivity of current outcome measures to detect subtle changes. Multiple breath washout is a potential sensitive test that is a useful readout of disease at these early stages but it lacks standardisation and knowledge of variability with reference to standard lung function measures. This is a Cross sectional and longitudinal observation study. The hypothesis is that multiple breath washout-derived indices will provide a robust signal of gas mixing inhomogeneity, correlating with conventional measures of airway disease severity. Multiple breath washout performed on different devices will generate indices which correlate but differ in value.

Conditions

Interventions

DEVICE

Multiple breath washout testing

Multiple breath washout testing will be completed on different devices over time

Sponsors & Collaborators

  • Imperial College London

    lead OTHER

Principal Investigators

  • Jane C Davies, Professor · Imperial College London

Eligibility

Min Age
2 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-05-05
Primary Completion
2024-03-31
Completion
2024-03-31
FDA Device
Yes

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03320382 on ClinicalTrials.gov