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Role of Oxygen for Vascular Dysfunction

NCT02127333 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 38

Last updated 2014-12-16

No results posted yet for this study

Summary

Hypoxemia may contribute increased morbidity and mortality in chronic obstructive pulmonary disease (COPD) patients. We aim to characterize the role of acute and chronic hypoxemia for vascular function. For this purpose we measure capillary oxygen concentration and vascular.

Vascular function is assessed by flow-mediated dilation oft he brachial artery, forearm blood flow and laser doppler perfusion imaging.

We hypothesize that hypoxemia leads to impaired vascular function.

Conditions

  • Endothelial Dysfunction
  • FMD
  • IMT
  • Microcirculation
  • Oxygen Pressure
  • Carbon Dioxide Pressure
  • Oxygen Saturation
  • Forced Expiratory Volume After 1 Second

Sponsors & Collaborators

  • Klinik für Kardiologie, Pneumologie und Angiologie

    lead OTHER

Principal Investigators

  • Christian Heiss, MD · Division of Cardiology, Pulmonary Disease and Vascular Medicine

  • Malte Kelm, MD · Division of Cardiology, Pulmonary Disease and Vascular Medicineine

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-01-31
Primary Completion
2013-09-30
Completion
2013-09-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02127333 on ClinicalTrials.gov