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Impact of Physical Activity on Left Ventricular Mass and Lipid Metabolism

NCT01199211 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 187

Last updated 2020-07-31

No results posted yet for this study

Summary

Prospective study on the structural and functional changes in the heart of adult women assessed by echocardiogram and in lipid metabolism that occur in response to physical training. Using echocardiogram we will characterize the early determinants of "athletic remodeling". We will also assess the effect of intense physical training on lipid metabolism, focus on HDL subspecies and function.

Conditions

  • Left Ventricular Hypertrophy

Interventions

OTHER

Exercise training, women, marathon

Prospective study with no intervention in women who have volunteered to run a full marathon or a half-marathon. Each subject will serve as own control. Each subject will be studies at 3 stages: baseline, after at least 12 weeks of training for the marathon (we will not provide training), 6 weeks after running the marathon.

Sponsors & Collaborators

Principal Investigators

  • Eveline Stock, MD · University of California, San Francisco

  • Nelson Schiller, MD · University of California, San Francisco

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-02-28
Primary Completion
2017-10-31
Completion
2017-10-31

Countries

  • United States

Study Locations

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Entities

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01199211 on ClinicalTrials.gov