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Relation of Obesity With Frequency of Meals (MST 0557)

NCT00229255 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2012-06-01

No results posted yet for this study

Summary

The purpose of this study is to test the relationship between frequency of meals and hepatic fat content and insulin sensitivity. We, the researchers at Rockefeller University, hypothesize that low plasma insulin levels (as achieved by periods of fasting) will prevent insulin resistance and reduce hepatic lipid content. In contrast, frequent, carbohydrate-rich meals will predispose to hepatic steatosis (non-alcoholic) and insulin resistance.

This is a 6 week inpatient study.

Conditions

Interventions

OTHER

high frequency of meals

high carbohydrate diet i.e. 65% carbohydrate, 15% protein, 20% fat for 4 weeks.

OTHER

twice a day meals

high carbohydrate diet i.e. 65% carbohydrate, 15% protein, 20% fat for 4 weeks.

Sponsors & Collaborators

Principal Investigators

  • Markus Stoffel, MD, PHD · Rockefeller University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-03-31
Primary Completion
2009-06-30
Completion
2009-06-30

Countries

  • United States

Study Locations

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Diseases
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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00229255 on ClinicalTrials.gov