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ENIGMA - Evaluation of Nitrous Oxide In the Gas Mixture for Anaesthesia: a Randomised Controlled Trial

NCT00164047 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 2070

Last updated 2009-07-31

No results posted yet for this study

Summary

We aim to investigate the effectiveness and safety of nitrous oxide (N2O) in anaesthesia.

Hypothesis In patients undergoing anaesthesia for major surgery, avoidance of N2O will reduce hospital length of stay when compared with otherwise identically managed surgical patients receiving N2O as a component of their anaesthesia.

Conditions

  • Quality of Recovery From Anaesthesia
  • Effects of Nitrous Oxide Following Anaesthesia
  • Induced Endothelial Dysfunction

Interventions

DRUG

Nitrous Oxide

Sponsors & Collaborators

  • National Health and Medical Research Council, Australia

    collaborator OTHER

  • Australia: Theapeutic Goods Administration

    collaborator OTHER_GOV

  • Bayside Health

    lead OTHER_GOV

Principal Investigators

  • Paul S Myles, MB BS MPH MD · The Alfred

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-04-30
Primary Completion
2004-12-31
Completion
2004-12-31

Countries

  • Australia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00164047 on ClinicalTrials.gov