MedTrace Logo

Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13

NCT00000261 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2015-05-27

No results posted yet for this study

Summary

The purpose of this study is to evaluate the effects of alcohol history on the subjective and reinforcing effects of sevoflurane and nitrous oxide in healthy volunteers. All subjects underwent psychomotor testing during 4 sessions of placebo, drug/placebo, and choice of intervention.

Conditions

  • Alcohol-Related Disorders
  • Opioid-Related Disorders
  • Substance-Related Disorders

Interventions

DRUG

30% Nitrous oxide

OTHER

Placebo

No drug (100% oxygen)

DRUG

0.2% sevoflurane

DRUG

0.4% sevoflurane

DRUG

0.6% sevoflurane

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • University of Chicago

    lead OTHER

Principal Investigators

  • James Zacny, Ph.D. · University of Chicago

Study Design

Allocation
NA
Masking
DOUBLE
Model
SINGLE_GROUP

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1997-11-30
Primary Completion
1998-10-31
Completion
1998-10-31

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00000261 on ClinicalTrials.gov