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The Effect of N2O Administration on Arterial Oxygenation

NCT00146250 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2018-01-11

No results posted yet for this study

Summary

Nitrous oxide is a standard part of most anaesthetic breathing mixtures. It has often been assumed that it reduces the amount of oxygen reaching the lower parts of the lung. However the results of previous studies and of some computer modelling suggests the opposite may be true, and that oxygen levels in the blood are actually higher with nitrous oxide. This study seeks to determine whether nitrous oxide increases or decreases blood oxygen levels in anaesthetized patients.

Conditions

  • Anesthesia

Interventions

DRUG

Nitrous oxide

Substitution of Nitrous oxide for Nitrogen as balance gas in inspired gas mixture

Sponsors & Collaborators

Principal Investigators

  • Philip J Peyton, MD FANZCA · Dept of Anaesthesia, Austin Health

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-03-01
Primary Completion
2005-07-20
Completion
2005-09-30
FDA Drug
Yes

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00146250 on ClinicalTrials.gov