Beta-CIT-SPECT and Neurophysiology in Depression
NCT00145132 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2010-06-02
Summary
Aim of this project is to investigate the effects of escitalopram on monoamine transporter (SERT, DAT) availabilities as assessed by b-CIT and SPECT, and on neurophysiological parameters such as the loudness dependence of auditory evoked potentials (LDAEP) in patients with depression.
Conditions
Interventions
- PROCEDURE
-
β-CIT-SPECT, Neurophysiology
β-CIT-SPECT scans and EEG recordings, two assessments each
Sponsors & Collaborators
-
H. Lundbeck A/S
collaborator INDUSTRY -
Ludwig-Maximilians - University of Munich
lead OTHER
Principal Investigators
-
Oliver Pogarell, MD · Dept. of Psychiatry, University of Munich
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-06-30
- Primary Completion
- 2009-12-31
- Completion
- 2009-12-31
Countries
- Germany
Study Locations
More Related Trials
-
Prediction of the Therapeutic Response in Depression Based on Neuro-computational Modeling Assessment of Motivation
NCT05866575 ·Status: RECRUITING ·Phase: NA
-
Study of Brain Response to Emotional Pictures Using a Magnetic Resonance Imaging (fMRI) While on Escitalopram
NCT00707863 ·Status: COMPLETED ·Phase: PHASE4
-
Cognitive Behavioural Analysis System of Psychotherapy (CBASp) Versus Escitalopram in Chronic Depression
NCT00837564 ·Status: UNKNOWN ·Phase: PHASE3
-
The Role of Serotonin in Compulsive Behavior in Humans: Underlying Brain Mechanisms
NCT04336228 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Biological Markers of Response to Treatment in Major Depressive Disorder
NCT00361218 ·Status: COMPLETED ·Phase: PHASE3
-
Serotonergic Modulation of Cognition, Emotion and Brain Activation in Healthy Volunteers
NCT04239339 ·Status: COMPLETED ·Phase: PHASE4
-
Brain Effects of Escitalopram and Citalopram Using fMRI
NCT00825825 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of SERT Inhibition on the Subjective Response to LSD in Healthy Subjects
NCT05175430 ·Status: COMPLETED ·Phase: PHASE1
-
Brain Activity Changes and Treatment Response in Depressed People Who Are Receiving Antidepressant Medication
NCT00375843 ·Status: COMPLETED ·Phase: PHASE4
-
Study of Neural Responses Induced by Antidepressant Effects
NCT02674529 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Exploring Biomarkers for Depression
NCT01424111 ·Status: COMPLETED
-
Brain Network Dynamics of Depression During Esketamine Treatment
NCT06012916 ·Status: COMPLETED
-
Study of Electrophysiological Markers of Antidepressants in Major Depressive Disorder
NCT06532604 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Neural Responses and Dysphoria: Modulation by a Pharmacological Probe
NCT01101685 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Antidepressant Therapy on Brain Dopamine Transporter Activity in People With Major Depression
NCT00655057 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Patient Stratification and Treatment Response Prediction in Neuropharmacotherapy Using Hybrid Positron Emmission Tomography/Magnetic Resconance Imaging (PET/MR)
NCT02711215 ·Status: UNKNOWN ·Phase: PHASE4
-
Mechanism of Antidepressant-Related Dysfunctional Arousal in High-Risk Youth
NCT02553161 ·Status: COMPLETED ·Phase: NA
-
A Neuroimaging and Epigenetic Investigation of Antidepressants in Depression
NCT00703742 ·Status: COMPLETED ·Phase: NA
-
The Effect of SSRIs on Threat of Shock Potentiated Neural Circuitry
NCT07074652 ·Status: COMPLETED ·Phase: NA
-
An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression
NCT00070694 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of Depression Symptoms and Brain Activity Associated With Response to Treatment of Depression
NCT00200902 ·Status: COMPLETED ·Phase: PHASE4
-
Neurotrophic Factors and Depression
NCT00812994 ·Status: COMPLETED ·Phase: PHASE4
-
Imaging Predictors of Treatment Response in Depression
NCT00367341 ·Status: COMPLETED ·Phase: NA
-
Pre-Treatment Positron Emission Topography Scanning for Increasing Success in Antidepressant Treatment
NCT00456014 ·Status: COMPLETED ·Phase: NA
-
Effects of SERT Inhibition on the Subjective Response to Psilocybin in Healthy Subjects
NCT03912974 ·Status: COMPLETED ·Phase: PHASE1