Study of Neural Responses Induced by Antidepressant Effects

NCT02674529 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2022-11-03

Study results available
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Summary

The proposed work aims to examine the neural changes associated with fast-acting antidepressant treatments in order to develop imaging-based biomarkers of treatment response for depression.

Conditions

Interventions

DRUG

Escitalopram

Selective Serotonin Reuptake Inhibitor (SSRI)

DRUG

Placebo

Placebo

BEHAVIORAL

Real-time Neurofeedback fMRI task pre- and post-RCT

Placebo experiment during an fMRI scanning session

Sponsors & Collaborators

  • Marta Peciña, MD PhD

    lead OTHER

Principal Investigators

  • Marta Pecina, MD, PhD · University of Pittsburgh

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-09-30
Primary Completion
2021-05-31
Completion
2021-05-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02674529 on ClinicalTrials.gov