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Neurotrophic Factors and Depression

NCT00812994 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2008-12-22

No results posted yet for this study

Summary

Study intended to determine if there are baseline differences in serum neurosteroid levels and neurotrophic factor (BDNF) levels in healthy controls vs unmedicated depressed subjects, and whether the levels of these change with antidepressant treatment. Study also intended to determine if baseline neurosteroid/ BDNF levels, and the change in these levels with =treatment, are correlated with clinical antidepressant response to escitalopram (Lexapro).

Conditions

Interventions

DRUG

Escitalopram

SSRI antidepressant

DRUG

Placebo

Sponsors & Collaborators

Principal Investigators

  • Owen M Wolkowitz, MD · University of California, San Francisco

Study Design

Purpose
BASIC_SCIENCE
Masking
DOUBLE

Eligibility

Min Age
22 Years
Max Age
55 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2003-01-31
Primary Completion
2006-12-31
Completion
2008-11-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00812994 on ClinicalTrials.gov