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Combination Chemotherapy Before Surgery in Treating Children With Localized Neuroblastoma

NCT00025428 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2013-12-04

No results posted yet for this study

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs before surgery may shrink the tumor so that it can be removed during surgery.

PURPOSE: Phase III trial to determine the effectiveness of combination chemotherapy given before surgery in treating children who have localized neuroblastoma.

Conditions

Interventions

DRUG

carboplatin

DRUG

cyclophosphamide

DRUG

doxorubicin hydrochloride

DRUG

etoposide

DRUG

vincristine sulfate

PROCEDURE

adjuvant therapy

PROCEDURE

conventional surgery

PROCEDURE

neoadjuvant therapy

Sponsors & Collaborators

  • Children's Cancer and Leukaemia Group

    collaborator OTHER

  • Societe Internationale d'Oncologie Pediatrique

    lead OTHER

Principal Investigators

  • Janice A. Kohler, MD, FRCP · University Hospital Southampton NHS Foundation Trust

Study Design

Purpose
TREATMENT

Eligibility

Min Age
1 Year
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2000-12-31
Completion
2013-11-30

Countries

  • Austria
  • Belgium
  • Denmark
  • France
  • Germany
  • Italy
  • Norway
  • Portugal
  • Spain
  • Sweden
  • Switzerland
  • United Kingdom

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00025428 on ClinicalTrials.gov