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Combination Chemotherapy Followed by Surgery and Peripheral Stem Cell or Bone Marrow Transplantation in Treating Infants With Newly Diagnosed Neuroblastoma

NCT00025649 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL

Last updated 2013-09-17

No results posted yet for this study

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell or bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells.

PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy given before surgery followed by peripheral stem cell or bone marrow transplantation in treating infants who have newly diagnosed neuroblastoma.

Conditions

Interventions

BIOLOGICAL

filgrastim

DRUG

busulfan

DRUG

carboplatin

DRUG

cyclophosphamide

DRUG

doxorubicin hydrochloride

DRUG

etoposide

DRUG

melphalan

DRUG

vincristine sulfate

PROCEDURE

autologous bone marrow transplantation

PROCEDURE

conventional surgery

PROCEDURE

peripheral blood stem cell transplantation

Sponsors & Collaborators

  • European Infant Neuroblastoma Study Group - 1999

    lead OTHER

Principal Investigators

  • Adela Canete, MD, PhD · Hospital Universitario La Fe

Study Design

Purpose
TREATMENT

Eligibility

Max Age
1 Year
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1999-07-31
Completion
2009-03-31

Countries

  • Austria
  • Belgium
  • Denmark
  • France
  • Italy
  • Norway
  • Portugal
  • Spain
  • Sweden
  • Switzerland
  • United Kingdom

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00025649 on ClinicalTrials.gov