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Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Head and Neck Cancer

NCT00002476 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL

Last updated 2013-08-02

No results posted yet for this study

Summary

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if radiation therapy plus chemotherapy is more effective than radiation therapy alone in treating patients with advanced head and neck cancer.

PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without chemotherapy in treating patients with advanced head and neck cancer.

Conditions

Interventions

BIOLOGICAL

bleomycin sulfate

DRUG

fluorouracil

DRUG

leucovorin calcium

DRUG

methotrexate

DRUG

vincristine sulfate

RADIATION

low-LET cobalt-60 gamma ray therapy

RADIATION

low-LET photon therapy

RADIATION

radiation therapy

Sponsors & Collaborators

Principal Investigators

  • Jeffrey S. Tobias, MD · University College London Hospitals

Study Design

Purpose
TREATMENT

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1990-01-31
Completion
2010-01-31

Countries

  • India
  • United Kingdom

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00002476 on ClinicalTrials.gov