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Radiation Therapy and Chemotherapy in Treating Patients With Head and Neck Cancer

NCT00002507 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL

Last updated 2013-07-25

No results posted yet for this study

Summary

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether combining mitomycin or porfiromycin with radiation therapy is more effective in treating patients with head and neck cancer.

PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy plus either mitomycin or porfiromycin in treating patients with head and neck cancer.

Conditions

Interventions

DRUG

mitomycin C

DRUG

porfiromycin

RADIATION

brachytherapy

RADIATION

radiation therapy

Sponsors & Collaborators

  • Yale University

    lead OTHER

Principal Investigators

  • James J. Fischer, MD, PhD · Yale University

Study Design

Purpose
TREATMENT

Eligibility

Min Age
20 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1992-11-30
Primary Completion
2002-10-31
Completion
2002-10-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00002507 on ClinicalTrials.gov