Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Advanced Cancer of the Mouth, Pharynx, or Larynx
NCT00004094 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2014-01-06
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining radiation therapy with chemotherapy may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus radiation therapy in treating patients who have previously untreated advanced cancer of the mouth, pharynx, or larynx.
Conditions
Interventions
- DRUG
- DRUG
- DRUG
-
hydroxyurea
- DRUG
- PROCEDURE
-
conventional surgery
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Athanassios Argiris, MD · Robert H. Lurie Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 15 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-08-31
Countries
- United States
Study Locations
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