Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Larynx or Oropharynx Cancer
NCT00014118 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2023-06-15
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by radiation therapy and chemotherapy in treating patients who have stage III or stage IV cancer of the larynx or stage III or stage IV cancer of the oropharynx.
Conditions
Interventions
- DRUG
- DRUG
- PROCEDURE
-
conventional surgery
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Eastern Cooperative Oncology Group
lead NETWORK
Principal Investigators
-
Anthony J. Cmelak, MD · Vanderbilt-Ingram Cancer Center
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-06-06
- Primary Completion
- 2007-03-31
- Completion
- 2009-05-31
Countries
- United States
Study Locations
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