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Effects of Sevoflurane in Subanesthetic Concentrations on the Forearm Perfusion

NCT00526695 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2008-07-18

No results posted yet for this study

Summary

Sevoflurane preconditioning and cardiovascular protection against ischemia/reperfusion injury.

Study hypothesis: The volatile anesthetic sevoflurane at subanesthetic concentrations achieves endothelial protection against ischemia/reperfusion injury and reduces inflammatory markers in the circulation

Conditions

  • Ischemia/Reperfusion Injury

Interventions

DRUG

Sevoflurane (Preconditioning)

Inhalation of sub-anesthetic doses of sevoflurane

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Michael Zaugg, PD Dr. med. · UniversitaetsSpital Zuerich

  • Michael Zaugg, PD Dr. med. · University of Zurich

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
25 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-01-31
Primary Completion
2008-12-31
Completion
2008-12-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00526695 on ClinicalTrials.gov