Also known as: crack cocaine, crack-cocaine
Cocaine is a tropane alkaloid with stimulant and local anesthetic properties. Although widely known for illicit use, pharmaceutical cocaine formulations are used medically in limited settings such as topical anesthesia. In the U.S., cocaine-containing products are controlled Schedule II substances.
A Florida recidivist with a prior federal drug conviction and a Pennsylvania woman pleaded guilty to separate drug trafficking charges involving crack cocaine, methamphetamine, and synthetic cannabinoids. The Florida defendant faces at least 10 years to life, with sentencing set for September 3, 2026.
Drug investigations and traffic stops across six states led to arrests and seizures of methamphetamine, cocaine, firearms, and paraphernalia. Charges include possession with intent to distribute, firearm offenses, and tampering with evidence.
Drug investigations in Missouri, Kentucky, Ohio, Iowa, and Georgia led to multiple arrests and seizures of methamphetamine, fentanyl, and cocaine. Authorities found over 10 pounds of meth in one case and filed trafficking and possession charges.
Delaware State Police arrested a Newark man on felony drug charges after a traffic stop in Townsend. Officers seized crack cocaine, cocaine, heroin, and over $2,200 in suspected drug proceeds.
Recent drug investigations in New York and New Jersey led to more than a dozen arrests and seizures of fentanyl, cocaine, guns, and cash. Cases in Jersey City, Syracuse, Fallsburg, and Monticello resulted in numerous drug charges.
An Ontario investigation yielded nearly 1.7 tonnes of drugs valued at over $139 million and 21 people charged. Other probes in four U.S. states led to more arrests and seizures.
Four women face drug-related charges after traffic stops in four states, with seizures of meth, cocaine, prescription drugs, and fake IDs. Charges range from possession to drug sales and identity fraud.
Law enforcement in three states arrested 11 people in separate drug investigations, seizing cocaine, methamphetamine, fentanyl, LSD, firearms and body armor. The arrests followed anonymous tips, a police pursuit, a traffic stop and search warrants.
Drug enforcement actions in several states led to seizures of meth, heroin, cocaine, and firearms. A Fort Worth man received a 40-year prison sentence, six men were charged in Nassau County, and a corrections officer was arrested.
Trump signed a new counterterrorism strategy prioritizing Western Hemisphere cartels. The National Drug Control Strategy 2026 pressures Mexico and Colombia, and the administration is working with social media platforms to disrupt cartel drug sales to children.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT05809453 |
Intranasal Cocaine and Temperature Regulation During Exercise |
COMPLETED | PHASE1/PHASE2 |
| NCT05019430 |
Cocaine and Zolmitriptan |
COMPLETED | EARLY_PHASE1 |
| NCT03954938 |
Behavioral Effects of Drugs (Inpatient): 38 |
TERMINATED | EARLY_PHASE1 |
| NCT03937986 |
Suvorexant and Cocaine |
COMPLETED | EARLY_PHASE1 |
| NCT03519022 |
Behavioral Effects of Drugs: Inpatient (35) |
COMPLETED | EARLY_PHASE1 |
| NCT02538744 |
Complementary Combination Therapy for Cocaine Dependence |
COMPLETED | PHASE1 |
| NCT02522325 |
Reinforcing Effects of Cocaine During Phendimetrazine Maintenance |
COMPLETED | PHASE1 |
| NCT02383043 |
Impact of Sustained Release d-Amphetamine on Choice Between Cocaine and a Non-Drug Reinforcer |
COMPLETED | EARLY_PHASE1 |
| NCT02239913 |
Topiramate-Phentermine Combinations for Cocaine Dependence |
COMPLETED | PHASE1 |
| NCT02233647 |
Phendimetrazine and Cocaine |
COMPLETED | EARLY_PHASE1 |
