Also known as: crack cocaine
Cocaine is a tropane alkaloid with stimulant and local anesthetic properties. Although widely known for illicit use, pharmaceutical cocaine formulations are used medically in limited settings such as topical anesthesia. In the U.S., cocaine-containing products are controlled Schedule II substances.
New court documents link the Project South police corruption probe to alleged Ryan Wedding drug ring associate Gurpreet Singh, while separate U.S. filings accuse "cocaine lawyer" Deepak Paradkar of helping Wedding's organization.
Two major drug trafficking investigations in North Carolina and Tennessee have led to over 30 arrests combined. The North Carolina case resulted in more than 170 charges after seizing cocaine, fentanyl, methamphetamine, guns and cash. In Tennessee, 15 individuals were indicted for conspiring to distribute cocaine, with seizures including fentanyl, marijuana, cocaine, methamphetamine, firearms and cash.
Three recent drug enforcement operations in Virginia and Alabama led to multiple arrests and seizures of cocaine, fentanyl, methamphetamine, firearms, and over $3,000 in cash. The cases involved separate investigations by county sheriff's offices and drug task forces.
Newport Police arrested four people after a month-long drug investigation culminated in a search warrant execution. Authorities seized cocaine laced with fentanyl and thousands of dollars in cash. All four suspects are expected in court Wednesday afternoon.
Vancouver police seized over $79,000 in illicit drugs, cash, and weapons during a six-month investigation called "Project Bingo" targeting drug trafficking on the Downtown Eastside. The search uncovered fentanyl, cocaine, methamphetamine, dilaudid pills, illegal cigarettes, and a large cache of weapons. A 61-year-old man was arrested and released pending further investigation.
South African authorities have executed multiple major drug enforcement operations, including a R250 million crystal meth lab bust in the North West and a network disruption in Gqeberha. These actions are part of an ongoing crackdown on organised drug crime.
Drug-soaked paper has become the most commonly found drug in Ohio prisons and was tied to at least 13 fatal K2 overdoses in 2024. Convictions in the state’s largest prison drug conspiracy case detailed how the paper was smuggled and sold.
Police in Karachi, Kentucky and Indiana arrested three suspects in separate drug investigations involving alleged trafficking in Ice, methamphetamine and cocaine. One case involved a controlled purchase, while another led to the seizure of nearly 60 grams of cocaine and a firearm.
More than 2,700 drivers were arrested for drug-related offences in January as authorities expanded roadside inspections and medical testing. Separate road safety checks in Keighley recorded 17 offences, including one drug-driving arrest.
Laurel police said four people were arrested and one more is wanted after a two-month-long drug investigation. Officers said they found heroin, cocaine, crack cocaine and a .38 caliber handgun at a Laurel apartment complex home.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT05809453 |
Intranasal Cocaine and Temperature Regulation During Exercise |
COMPLETED | PHASE1/PHASE2 |
| NCT05019430 |
Cocaine and Zolmitriptan |
COMPLETED | EARLY_PHASE1 |
| NCT03954938 |
Behavioral Effects of Drugs (Inpatient): 38 |
TERMINATED | EARLY_PHASE1 |
| NCT03937986 |
Suvorexant and Cocaine |
COMPLETED | EARLY_PHASE1 |
| NCT03519022 |
Behavioral Effects of Drugs: Inpatient (35) |
COMPLETED | EARLY_PHASE1 |
| NCT02538744 |
Complementary Combination Therapy for Cocaine Dependence |
COMPLETED | PHASE1 |
| NCT02522325 |
Reinforcing Effects of Cocaine During Phendimetrazine Maintenance |
COMPLETED | PHASE1 |
| NCT02383043 |
Impact of Sustained Release d-Amphetamine on Choice Between Cocaine and a Non-Drug Reinforcer |
COMPLETED | EARLY_PHASE1 |
| NCT02239913 |
Topiramate-Phentermine Combinations for Cocaine Dependence |
COMPLETED | PHASE1 |
| NCT02233647 |
Phendimetrazine and Cocaine |
COMPLETED | EARLY_PHASE1 |
