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Clinical Trials

Showing trials with last updates posted in 2026.

NCT04160507 | RECRUITING
200 participants

Duke APOL1 Research Biorepository

Study Type:
OBSERVATIONAL
Last Updated:
2026-08-27
Start Date:
2019-12-13
Completion:
2026-11-15
Conditions
  • End Stage Kidney Disease
Interventions
  • OTHER
No Results Yet
NCT04158648 | COMPLETED | PHASE3
73 participants

A Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Emicizumab in Participants With Mild or Moderate Hemophilia A Without FVIII Inhibitors

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-27
Start Date:
2020-02-10
Completion:
2021-10-30
Conditions
  • Mild Hereditary Factor VIII Deficiency Disease Without Inhibitor
  • Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor
  • Hemophilia A
Interventions
  • DRUG
Results Available
NCT04077723 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
498 participants

A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-27
Start Date:
2019-08-13
Completion:
2027-03-31
Conditions
  • Lymphoma, Non-Hodgkin
Interventions
  • DRUG
No Results Yet
NCT03975829 | ACTIVE_NOT_RECRUITING | PHASE4
163 participants

Pediatric Long-Term Follow-up and Rollover Study

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-27
Start Date:
2019-11-04
Completion:
2026-11-05
Conditions
  • Diffuse Astrocytoma
  • Anaplastic Astrocytoma
  • Astrocytoma
  • Oligodendroglioma, Childhood
  • Anaplastic Oligodendroglioma
  • Glioblastoma
  • Pilocytic Astrocytoma
  • Giant Cell Astrocytoma
  • Pleomorphic Xanthoastrocytoma
  • Anaplastic Pleomorphic Xanthoastrocytoma
  • Angiocentric Glioma
  • Chordoid Glioma of Third Ventricle
  • Gangliocytoma
  • Ganglioglioma
  • Anaplastic Ganglioglioma
  • Dysplastic Gangliocytoma of Cerebrellum
  • Desmoplastic Infantile Astrocytoma and Ganglioglioma
  • Papillary Glioneuronal Tumor
  • Rosette-forming Glioneuronal Tumor
  • Central Neurocytoma
  • Extraventricular Neurocytoma
  • Cerebellar Liponeurocytoma
  • Neurofibromatosis Type 1
Interventions
  • DRUG
No Results Yet
NCT03953846 | TERMINATED
36 participants

NUsurface Implant Registry

Study Type:
OBSERVATIONAL
Last Updated:
2026-08-27
Start Date:
2019-06-01
Completion:
2023-11-01
Conditions
  • Meniscus; Degeneration
  • Knee Osteoarthritis
  • Knee Pain Chronic
No Results Yet
NCT03816319 | SUSPENDED | PHASE1
42 participants

TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes With Increased Blasts

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-27
Start Date:
2025-03-12
Completion:
2026-10-24
Conditions
  • Myelodysplastic Syndrome With Excess Blasts
  • Recurrent Acute Myeloid Leukemia
  • Recurrent Myelodysplastic Syndrome
  • Recurrent Myelodysplastic Syndrome/Acute Myeloid Leukemia
  • Refractory Acute Myeloid Leukemia
  • Refractory Myelodysplastic Syndrome
  • Refractory Myelodysplastic Syndrome/Acute Myeloid Leukemia
Interventions
  • PROCEDURE
  • DRUG
No Results Yet
NCT03811002 | ACTIVE_NOT_RECRUITING | PHASE3
544 participants

Testing the Addition of a New Immunotherapy Drug, Atezolizumab (MPDL3280A), to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Stage Small Cell Lung Cancer (LS-SCLC)

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-27
Start Date:
2019-07-26
Completion:
2024-04-21
Conditions
  • Limited Stage Lung Small Cell Carcinoma
  • Stage I Lung Cancer AJCC v8
  • Stage II Lung Cancer AJCC v8
  • Stage III Lung Cancer AJCC v8
Interventions
  • RADIATION
  • DRUG
  • PROCEDURE
  • OTHER
Results Available
NCT03258554 | COMPLETED | PHASE2/PHASE3
196 participants

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-27
Start Date:
2018-04-03
Completion:
2022-09-20
Conditions
  • Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
  • Head and Neck Squamous Cell Carcinoma
  • Hypopharyngeal Squamous Cell Carcinoma
  • Laryngeal Squamous Cell Carcinoma
  • Oral Cavity Squamous Cell Carcinoma
  • Oropharyngeal Squamous Cell Carcinoma
  • Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
  • Squamous Cell Carcinoma of Unknown Primary
  • Stage III Hypopharyngeal Carcinoma AJCC v8
  • Stage III Laryngeal Cancer AJCC v8
  • Stage III Lip and Oral Cavity Cancer AJCC v8
  • Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
  • Stage IVA Hypopharyngeal Carcinoma AJCC v8
  • Stage IVA Laryngeal Cancer AJCC v8
  • Stage IVA Lip and Oral Cavity Cancer AJCC v8
  • Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
  • Stage IVB Hypopharyngeal Carcinoma AJCC v8
  • Stage IVB Laryngeal Cancer AJCC v8
  • Stage IVB Lip and Oral Cavity Cancer AJCC v8
  • Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions
  • BIOLOGICAL
  • RADIATION
  • OTHER
Results Available
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