Study of Immune Responses to Influenza Vaccination
NCT03346772 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 75
Last updated 2025-08-19
Summary
Better understanding of the immune responses to influenza vaccination is needed in order to understand situations of poor vaccine response. Adults will receive influenza vaccination and then have peripheral blood drawn at pre-defined intervals in order to study the lymphocyte responses.
Conditions
- Influenza Vaccination
Interventions
- BIOLOGICAL
-
Influenza vaccination
Adults will receive one intramuscular dose of seasonal quadrivalent inactivated influenza vaccine, as indicated for standard of care.
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
E.John Wherry, PhD · University of Pennsylvania
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-10-20
- Primary Completion
- 2026-07-01
- Completion
- 2026-07-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
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