Photon Therapy Versus Proton Therapy in Early Tonsil Cancer.
NCT03829033 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2021-09-01
Summary
In this trial, patients with early squamous cell carcinoma of the tonsil with clinical stage T1-2 (p16-positive or p16-negative) N0-1 (p16-positive)/N0-N2b (p16-negative) according to American Joint Committee on Cancer (AJCC) 8th edition, aimed for unimodal and ipsilateral treatment with radiotherapy with curative intent will be included. The patients will be randomized to in a 1:1 ratio to receive radiotherapy with either photons (conventional radiotherapy) versus radiotherapy with protons.
Conditions
- Tonsil Cancer
Interventions
- RADIATION
-
Radiotherapy
Radiotherapy with either photons or protons.
Sponsors & Collaborators
-
Lund University Hospital
lead OTHER
Principal Investigators
-
Maria Gebre-Medhin, MD · Lund University Hospiyal
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-01-22
- Primary Completion
- 2028-01-31
- Completion
- 2028-01-31
Countries
- Sweden
Study Locations
More Related Trials
-
Vocal-cord vs. Complete Laryngeal Radiotherapy for Early Glottic Cancer
NCT03759431 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
TOMO Versus IMRT in Nasopharyngeal Carcinoma Patients
NCT03588403 ·Status: UNKNOWN
-
Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Cancer of the Larynx
NCT00002496 ·Status: COMPLETED ·Phase: PHASE3
-
Trial of Image-Guided Adaptive Conformal Photon vs Proton Therapy, With Concurrent Chemotherapy, for Locally Advanced Non-Small Cell Lung Carcinoma: Treatment Related Pneumonitis and Locoregional Recurrence
NCT00915005 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Randomized Study of Hypofractionated Versus Conventional Radiotherapy
NCT06080503 ·Status: RECRUITING ·Phase: NA
-
Hypofractionated Radiotherapy for Soft Tissue Sarcomas
NCT03972930 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of External Beam Radiotherapy to Thyroid Carcinoma
NCT01173289 ·Status: COMPLETED ·Phase: PHASE2
-
Hypofractionated vs. Conventionally Fractionated Concurrent CRT for LD-SCLC
NCT02688036 ·Status: UNKNOWN ·Phase: PHASE3
-
DENTOFACIAL-PBT Stage 2 - Feasibility Study
NCT07057284 ·Status: ENROLLING_BY_INVITATION
-
Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck
NCT01287390 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment
NCT07293247 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Proton Radiation for the Treatment of Pediatric Bone and Non-Rhabdomyosarcoma Soft Tissue Sarcomas
NCT00592293 ·Status: COMPLETED ·Phase: NA
-
Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors
NCT06349837 ·Status: RECRUITING ·Phase: PHASE1
-
Non-ablative Oligofractionated Radiation Therapy Before Surgical Transplantation As Radiovaccination
NCT04782752 ·Status: RECRUITING ·Phase: NA
-
Induction Chemotherapy Response-Guided Radiation for EBV-Associated Nasopharyngeal Carcinoma
NCT06682442 ·Status: RECRUITING ·Phase: NA
-
Testing the Safety of Giving a Standard Dose of Radiation Over a Shorter Period of Time for Patients Who Had Surgery for Intermediate-Risk Head and Neck Cancer
NCT05540899 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
a Multicentre Phase III Study of Risk-based Treatment Intensification With Hyperfractionated Radiotherapy in Head and Neck Cancer Patients
NCT06248996 ·Status: RECRUITING ·Phase: PHASE3
-
Moderate Hypofractionated Radiotherapy for Lung Cancer
NCT03833193 ·Status: UNKNOWN ·Phase: NA
-
Stereotactic Volumetric Radiotherapy in Prostate Cancer
NCT02423889 ·Status: COMPLETED ·Phase: PHASE2
-
The Role of Radiotherapy for the Management of Non-melanoma Skin Cancer in Denmark.
NCT07347392 ·Status: ENROLLING_BY_INVITATION
-
Impact of Hypofractionated Radiotherapy Strategy After Surgery of Skin Carcinomas in Older Patients
NCT05794035 ·Status: RECRUITING ·Phase: NA
-
Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection
NCT06189183 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Radiation Therapy to Treat Musculoskeletal Tumors
NCT00186992 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Involved-Field Radiation Therapy in Treating Patients With Previously Untreated Stage I or Stage II Low-Grade Non-Hodgkin's Lymphoma
NCT00014326 ·Status: TERMINATED ·Phase: PHASE3
-
Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial
NCT04883671 ·Status: RECRUITING ·Phase: NA