Clinical Trials

NCT04828226 | COMPLETED | PHASE4

130 participants

Clonidine to Prevent Delirium After Electroconvulsive Therapy.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-04-27

Completion:

2026-05-16

Conditions

• Major Depressive Disorder
• Catatonia
• Bipolar Disorder
• Delirium Postseizure

Interventions

• DRUG

No Results Yet

NCT04824794 | TERMINATED | PHASE1/PHASE2

130 participants

GEN3014 Trial in Relapsed or Refractory Hematologic Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-03-09

Completion:

2025-06-30

Conditions

• Relapsed or Refractory Multiple Myeloma (RRMM)
• Diffuse Large B Cell Lymphoma (DLBCL)
• Acute Myeloid Leukemia (AML)

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04806282 | RECRUITING

210 participants

Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2021-08-17

Completion:

2030-12-31

Conditions

• Meniere's Disease
• Enlarged Vestibular Aqueduct Syndrome
• Autoimmune Inner Ear Disease

No Results Yet

NCT04801420 | COMPLETED | PHASE2

625 participants

Phase 2 Study Of VLA15, A Vaccine Candidate Against Lyme Borreliosis, In A Healthy Pediatric And Adult Study Population

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-03-08

Completion:

2022-03-25

Conditions

• Lyme Borreliosis

Interventions

• BIOLOGICAL

Results Available

NCT04788524 | RECRUITING | NA

80 participants

Neural Correlates of Stress and Perceived Control in Adolescent Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-04-23

Completion:

2026-10-31

Conditions

• Major Depressive Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT04786821 | COMPLETED | NA

24 participants

Acceptability of Exoskeleton Assisted Walking for Persons With Mobility Issues Due to Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-06-23

Completion:

2024-10-30

Conditions

• Multiple Sclerosis
• Pathologic Processes
• Sclerosis
• Autoimmune Diseases of the Nervous System
• Demyelinating Autoimmune Diseases, CNS
• Autoimmune Diseases

Interventions

• BEHAVIORAL
• DEVICE

No Results Yet

NCT04762498 | COMPLETED | PHASE4

54 participants

A Phase 4, Open-label Study of KRYSTEXXA® (Pegloticase) Co-administered With Methotrexate (MTX) in Patients With Uncontrolled Gout (FORWARD OL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-01-26

Completion:

2023-05-18

Conditions

• Uncontrolled Gout
• Chronic Gout

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04737200 | RECRUITING | NA

30 participants

The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-02-08

Completion:

2027-03-31

Conditions

• Feeding Patterns
• Sleep
• Glucose Intolerance

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04708431 | RECRUITING

650 participants

Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2021-04-29

Completion:

2040-02-01

Conditions

• Androgen Insensitivity Syndrome
• Metabolic Parameters in AIS, CAIS, PAIS and MAIS
• Tumor Formation in AIS, CAIS, PAIS and MAIS
• Sexual Function AIS, CAIS, PAIS and MAIS

No Results Yet

NCT04703166 | RECRUITING

360 participants

Tulane iPredict, Prevent Study to Evaluate the Progression of Atrial Myopathy.

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2025-04-08

Completion:

2027-12-31

Conditions

• Atrial Fibrillation

Interventions

• DEVICE

No Results Yet

NCT04701515 | WITHDRAWN

0 participants

Cardiovascular Manifestations of COVID-19

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2023-03-21

Completion:

2023-07-03

Conditions

• COVID-19

Interventions

• OTHER

No Results Yet

NCT04696913 | COMPLETED

347 participants

Does COVID-19 Infection Increase the Risk of Pulmonary Embolism?

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2021-01-01

Completion:

2022-03-03

Conditions

• Covid19
• Pulmonary Embolism

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04662905 | RECRUITING | NA

200 participants

Novel Treatment Delivery of ECAP-controlled Closed-loop SCS for Chronic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-12-15

Completion:

2027-01-01

Conditions

• Chronic Pain

Interventions

• DEVICE

No Results Yet

NCT04649359 | ACTIVE_NOT_RECRUITING | PHASE2

187 participants

MagnetisMM-3: Study Of Elranatamab (PF-06863135) Monotherapy in Participants With Multiple Myeloma Who Are Refractory to at Least One PI, One IMiD and One Anti-CD38 mAb

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-02-02

Completion:

2022-06-17

Conditions

• Multiple Myeloma

Interventions

• DRUG

Results Available

NCT04635995 | COMPLETED | PHASE1

66 participants

Phase 1 Trial of LVGN7409 (CD40 Agonist Antibody) as Single Agent and Combination Therapies in Advanced or Metastatic Malignancy

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-12-11

Completion:

2025-12-31

Conditions

• Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT04586010 | ACTIVE_NOT_RECRUITING | PHASE3

746 participants

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-03-17

Completion:

2026-01-27

Conditions

• Relapsing Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT04581681 | COMPLETED | NA

72 participants

Group Cognitive Behavioural Therapy (CBT) For Perinatal Anxiety

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-12-02

Completion:

2023-01-30

Conditions

• Perinatal Anxiety

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04564625 | COMPLETED

100 participants

Relationships Between Vitamin D and Orthopedic Trauma

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2020-03-06

Completion:

2021-02-26

Conditions

• Fracture
• Fracture Nonunion
• Fractures, Bone
• Vitamin D

Interventions

• OTHER

No Results Yet

NCT04560543 | RECRUITING | NA

114 participants

Prophylactic Laparoscopic Suspension After McCall

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-05-15

Completion:

2027-04-30

Conditions

• Prolapse Pelvic

Interventions

• PROCEDURE

No Results Yet

NCT04546009 | ACTIVE_NOT_RECRUITING | PHASE3

992 participants

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-10-09

Completion:

2026-01-30

Conditions

• Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04514497 | ACTIVE_NOT_RECRUITING | PHASE1

29 participants

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-10-20

Completion:

2025-02-15

Conditions

• Metastatic Lung Small Cell Carcinoma
• Metastatic Malignant Solid Neoplasm
• Metastatic Neuroendocrine Carcinoma
• Metastatic Pancreatic Adenocarcinoma
• Stage III Lung Cancer AJCC v8
• Stage III Pancreatic Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8
• Stage IV Pancreatic Cancer AJCC v8
• Unresectable Lung Small Cell Carcinoma
• Unresectable Malignant Solid Neoplasm
• Unresectable Neuroendocrine Carcinoma
• Unresectable Pancreatic Adenocarcinoma

Interventions

• PROCEDURE
• DRUG

Results Available

NCT04505371 | COMPLETED | NA

234 participants

Improving the Reach & Effectiveness of Smoking Cessation Services Targeted to Veterans Living With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-06-04

Completion:

2025-03-31

Conditions

• HIV Infections
• Smoking
• Smoking Cessation

Interventions

• BEHAVIORAL

No Results Yet

NCT04488224 | WITHDRAWN | EARLY_PHASE1

0 participants

Nano-X Image Guidance: CBCT With Gravity-induced Motion

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2025-09-01

Completion:

2025-12-11

Conditions

• Cancer

Interventions

• DEVICE
• RADIATION
• OTHER

No Results Yet

NCT04477889 | COMPLETED

550 participants

Methodist Health System COVID-19 Patient Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2020-06-20

Completion:

2025-06-16

Conditions

• COVID-19

Interventions

• OTHER

No Results Yet

NCT04469855 | COMPLETED

3217 participants

Post-Marketing Surveillance (Special Use-results Surveillance) on Long-term Use With Ozempic®

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2020-07-27

Completion:

2025-05-12

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

No Results Yet

NCT04439292 | ACTIVE_NOT_RECRUITING | PHASE2

44 participants

Testing Trametinib and Dabrafenib as a Potential Targeted Treatment in Cancers With BRAF Genetic Changes (MATCH-Subprotocol H)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2016-01-04

Completion:

2023-11-27

Conditions

• Advanced Lymphoma
• Advanced Malignant Solid Neoplasm
• Hematopoietic and Lymphoid Cell Neoplasm
• Refractory Lymphoma
• Refractory Malignant Solid Neoplasm
• Refractory Multiple Myeloma

Interventions

• DRUG

Results Available

NCT04370236 | TERMINATED | PHASE2/PHASE3

79 participants

INB03 for the Treatment of Pulmonary Complications From COVID-19

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-10-21

Completion:

2021-10-13

Conditions

• COVID-19

Interventions

• DRUG

Results Available

NCT04348604 | COMPLETED | NA

36 participants

Improving Adherence in Adolescents and Young Adults With Bipolar Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-03-15

Completion:

2023-09-01

Conditions

• Bipolar Disorder

Interventions

• BEHAVIORAL

Results Available

NCT04346225 | RECRUITING | PHASE2

75 participants

Magnetic Resonance Imaging (MRI) With Hyperpolarized Pyruvate (13C) as Diagnostic Tool in Advanced Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-07-16

Completion:

2026-12-31

Conditions

• Prostate Cancer
• Advanced Prostate Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04333459 | COMPLETED | PHASE2

132 participants

Safety/Immunogenicity Hantaan Virus DNA Vaccine and Puumala Virus DNA Vaccine, For Prevention of HFRS

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-08-23

Completion:

2024-10-15

Conditions

• Hantaan Virus Nephropathy
• Puumala Virus Nephropathy

Interventions

• BIOLOGICAL

No Results Yet

NCT04329065 | RECRUITING | PHASE2

25 participants

Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-04-20

Completion:

2026-12-31

Conditions

• Anatomic Stage I Breast Cancer AJCC v8
• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8

Interventions

• BIOLOGICAL
• DRUG
• PROCEDURE

No Results Yet

NCT04318678 | RECRUITING | PHASE1

108 participants

CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-07-29

Completion:

2029-07-29

Conditions

• AML/MDS
• B-ALL
• T-ALL
• BPDCN

Interventions

• DRUG

No Results Yet

NCT04276480 | COMPLETED | NA

9 participants

Efficacy of Piperacillin-tazobactam as Empirical Antimicrobial Therapy for VAP Among ESBL-E Carriers.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2022-02-16

Completion:

2024-04-22

Conditions

• Enterobacteriaceae Infections

Interventions

• DRUG

No Results Yet

NCT04269902 | RECRUITING | PHASE3

247 participants

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2021-03-02

Completion:

2028-10-01

Conditions

• Chronic Lymphocytic Leukemia
• Small Lymphocytic Lymphoma

Interventions

• PROCEDURE
• BIOLOGICAL
• OTHER
• DRUG

No Results Yet

NCT04253392 | ACTIVE_NOT_RECRUITING

500 participants

RETHINK REFLUX Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2020-07-08

Completion:

2032-07-31

Conditions

• Gastroesophageal Reflux

Interventions

• DEVICE

No Results Yet

NCT04242498 | COMPLETED | PHASE3

509 participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-03-02

Completion:

2021-11-09

Conditions

• Hidradenitis Suppurativa

Interventions

• DRUG
• OTHER

Results Available

NCT04242446 | COMPLETED | PHASE3

505 participants

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-02-19

Completion:

2022-04-07

Conditions

• Hidradenitis Suppurativa

Interventions

• DRUG
• OTHER

Results Available

NCT04219800 | COMPLETED | NA

46 participants

Reduced Occupational Sitting in Type 2 Diabetes Using mHealth (Mobile Health)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-12-08

Completion:

2023-12-30

Conditions

• Diabetes Mellitus, Type 2

Interventions

• BEHAVIORAL

No Results Yet

NCT04213014 | ACTIVE_NOT_RECRUITING | NA

935 participants

Guys/Girls Opt for Activities for Life Trial (GOAL) to Increase Young Adolescents' Physical Activity and Healthy Eating

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-19

Start Date:

2020-09-26

Completion:

2026-04-30

Conditions

• Obesity, Adolescent

Interventions

• BEHAVIORAL

No Results Yet

NCT04197271 | COMPLETED

280 participants

Management of Acutely Symptomatic Hernia

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-19

Start Date:

2020-03-03

Completion:

2020-11-30

Conditions

• Hernia
• Emergencies
• Surgery--Complications

Interventions

• PROCEDURE
• OTHER

No Results Yet