Clinical Trials Updated in 2025

NCT04842929 | COMPLETED | NA

108 participants

Magnetic Randomized Trial in Elderly Depressed

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2019-01-16
Completion:: 2023-03-20

Conditions

Major Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT04827732 | TERMINATED | NA

15 participants

Hypofractionated Pencil-Beam Scanning Intensity-modulated Proton Therapy (IMPT) in Recurrent Rectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-05-04
Completion:: 2024-07-29

Conditions

Recurrent Rectal Cancer

Interventions

RADIATION
DEVICE

Results Available

NCT04825626 | NO_LONGER_AVAILABLE

An Expanded Access IND for the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-09-29

Conditions

Chronic Inflammatory Demyelinating Polyneuropathy

Interventions

BIOLOGICAL

No Results Yet

NCT04825613 | NO_LONGER_AVAILABLE

"Individual Patient Expanded Access IND to Treat Primary Lateral Sclerosis"

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-09-29

Conditions

Primary Lateral Sclerosis, Adult, 1

Interventions

BIOLOGICAL

No Results Yet

NCT04809025 | RECRUITING

510 participants

Comparation of Endoscopic Biopsy and Postoperative Specimen for the Molecular Diagnosis of Gastric Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-05-24
Completion:: 2026-09-01

Conditions

Stomach Neoplasms
Endoscopy
Biopsy
Pathology

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT04807842 | RECRUITING | NA

200 participants

Multi-Gyn ActiGel Plus for Treatment of Bacterial Vaginosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-06-11
Completion:: 2026-12-01

Conditions

Bacterial Vaginoses

Interventions

DEVICE

No Results Yet

NCT04803370 | COMPLETED | NA

55 participants

Efficacy of Reinforcing Standard Therapy in COVID-19 Patients With Repeated Transfusion of Convalescent Plasma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-07-08
Completion:: 2021-09-01

Conditions

Covid19

Interventions

OTHER

Results Available

NCT04801589 | RECRUITING | PHASE3

372 participants

Goal-Directed Sedation in Mechanically Ventilated Infants and Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-05-10
Completion:: 2026-04-17

Conditions

Delirium
Critical Illness
Sedation Complication
Executive Dysfunction
Post Traumatic Stress Disorder

Interventions

DRUG

No Results Yet

NCT04798066 | NO_LONGER_AVAILABLE

Intermediate Size Expanded Access Protocol for the Treatment of Post-COVID-19 Syndrome

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-09-29

Conditions

Post COVID-19 Syndrome

Interventions

BIOLOGICAL

No Results Yet

NCT04772378 | NO_LONGER_AVAILABLE

Intermediate Size Patient Population Expanded Access IND for the Treatment of Patients With Parkinson's Disease.

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-09-29

Conditions

Parkinson Disease

Interventions

BIOLOGICAL

No Results Yet

NCT04756648 | ACTIVE_NOT_RECRUITING | PHASE1

21 participants

Phase I Clinical Trial of CT0180 Cells in the Treatment of Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-03-10
Completion:: 2023-03-31

Conditions

Advanced Hepatocellular Carcinoma

Interventions

DRUG

No Results Yet

NCT04711811 | NO_LONGER_AVAILABLE

Individual Patient Expanded Access IND of HB-adMSCs for Chronic Musculoskeletal Pain.

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-09-29

Conditions

Chronic Pain

Interventions

BIOLOGICAL

No Results Yet

NCT04706429 | COMPLETED | PHASE2

154 participants

The Efficacy and Mechanism of Trientine in Patients With Hypertrophic Cardiomyopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-12-01
Completion:: 2024-04-30

Conditions

Hypertrophic Cardiomyopathy

Interventions

DRUG

No Results Yet

NCT04625946 | COMPLETED | PHASE4

117 participants

Metformin as an Adjunctive Therapy to Catheter Ablation in Atrial Fibrillation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-01-19
Completion:: 2025-07-01

Conditions

Atrial Fibrillation

Interventions

DRUG
BEHAVIORAL
DEVICE

No Results Yet

NCT04612465 | ACTIVE_NOT_RECRUITING | PHASE3

46 participants

Clinical Study to Evaluate Efficacy and Safety of ASC and Fibringlue or Fibringlue in Patients With Crohn's Fistula

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-01-09
Completion:: 2025-04-08

Conditions

Crohn's Fistula

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04604288 | NO_LONGER_AVAILABLE

Individual Patient Expanded Access IND of Autologous HB-adMSCS for the Treatment of Bilateral Knee Pain.

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-09-29

Conditions

Knee Pain Chronic
Osteo Arthritis Knee

Interventions

BIOLOGICAL

No Results Yet

NCT04595266 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

Chemoembolization (Lifepearls-Irinotecan) in Patients With Colorectal Cancer and Metastatic Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-06-29
Completion:: 2024-01-15

Conditions

Colorectal Cancer Metastatic
Liver Metastasis Colon Cancer

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04565691 | ACTIVE_NOT_RECRUITING | NA

100 participants

Bacteremia From Periodontal Treatment to Elucidate the Underpinnings of Sepsis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2019-02-25
Completion:: 2027-12-31

Conditions

Bacteremia
Periodontal Diseases
Sepsis
Heart Diseases

Interventions

PROCEDURE

No Results Yet

NCT04563143 | COMPLETED | NA

16 participants

Novel Paradigms of Deep Brain Stimulation for Movement Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-01-17
Completion:: 2023-09-07

Conditions

Parkinson Disease

Interventions

OTHER

No Results Yet

NCT04555161 | RECRUITING | NA

30 participants

Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-03-15
Completion:: 2025-10-31

Conditions

Pulmonary Arterial Hypertension
Pulmonary Hypertension
Right Heart Dysfunction

Interventions

DEVICE

No Results Yet

NCT04526951 | COMPLETED | PHASE3

81 participants

TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-10-30
Completion:: 2025-06-20

Conditions

Central Retinal Artery Occlusion

Interventions

DRUG

No Results Yet

NCT04514952 | NO_LONGER_AVAILABLE

Individual Patient Expanded Access IND of Autologous HBadMSCs for the Treatment of Amyotrophic Lateral Sclerosis

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-09-29

Conditions

Amyotrophic Lateral Sclerosis

Interventions

BIOLOGICAL

No Results Yet

NCT04497727 | COMPLETED

35 participants

Gut Organoid and Microbiome Interactions in Hypertension

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-03-05
Completion:: 2022-04-08

Conditions

Gut Inflammation
Hypertension

Interventions

OTHER

Results Available

NCT04481087 | ACTIVE_NOT_RECRUITING | NA

34 participants

Clinical Comparison of Different Adhesives in NCCLs

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2018-02-10
Completion:: 2018-05-10

Conditions

Tooth Wear

Interventions

DEVICE

No Results Yet

NCT04479267 | ACTIVE_NOT_RECRUITING | PHASE2

8 participants

Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Previously Untreated Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-08-21
Completion:: 2025-06-19

Conditions

Diffuse Large B-Cell Lymphoma
High Grade B-Cell Lymphoma w/MYC & BCL2 or BCL6 Rearrangements
High Grade B-Cell Lymphoma w/MYC, BCL2 & BCL6 Rearrangements
Double Expressor Lymphoma
High-grade B-cell Lymphoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04438525 | RECRUITING | NA

219 participants

Is the BAT Inhibition Able to Replace Sting Challenges? (BATIRS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-01-07
Completion:: 2026-09-30

Conditions

Vespid Venom Allergy

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT04427852 | COMPLETED | NA

80 participants

Nutrition, Vision, and Cognition in Sport Study: Beef

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-01-20
Completion:: 2020-12-31

Conditions

Cognitive Change
Nutrient Deficiency
Nutritional Anemia
Visual Spatial Processing
Diet, Healthy
Diet; Deficiency
Dietary Deficiency
Dietary B12 Deficiency
Dietary Zinc Deficiency
Dietary Vitamin B12 Deficiency Anemia
Dietary Deficiency of Selenium and Vitamin E

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04389437 | RECRUITING | NA

450 participants

OCT-Angiography and Adaptive Optics in Patients With Memory Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-06-26
Completion:: 2026-06-30

Conditions

Amnesia
Alzheimer Disease
Lewy Body Disease
Parkinsons Disease With Dementia

Interventions

PROCEDURE

No Results Yet

NCT04365569 | COMPLETED | NA

78 participants

Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-01-06
Completion:: 2024-05-16

Conditions

Breast Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT04284839 | RECRUITING | PHASE3

3500 participants

The Direct Oral Anticoagulation Versus Vitamin K Antagonist After Cardiac Surgery Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-07-18
Completion:: 2027-06-30

Conditions

Bleeding Post Cardiac Surgery
Indication for Anticoagulation

Interventions

DRUG

No Results Yet

NCT04264572 | COMPLETED | NA

600 participants

Project MiNT: Assessing the Impact of Food & Video-Based Nutrition Education on Patients With Poorly Controlled Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-01-21
Completion:: 2025-05-09

Conditions

Diabetes Mellitus, Type 2

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT04250194 | COMPLETED | NA

288 participants

Navigation Endoscopy to Reach Indeterminate Lung Nodules Versus Trans-Thoracic Needle Aspiration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-05-22
Completion:: 2024-06-10

Conditions

Lung Nodule

Interventions

DEVICE

Results Available

NCT04244942 | RECRUITING

300 participants

CERAMENT™| Bone Void Filler Device Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-03-30
Completion:: 2028-03-30

Conditions

Orthopedic Disorder

Interventions

DEVICE

No Results Yet

NCT04235491 | ACTIVE_NOT_RECRUITING

37000 participants

Longitudinal Coverage With Evidence Development Study on Micra AV Leadless Pacemakers (Micra AV CED)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-02-06
Completion:: 2029-06-30

Conditions

Bradycardia

No Results Yet

NCT04228666 | WITHDRAWN | PHASE1/PHASE2

0 participants

A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy (HB-adMSCs) for the Treatment of Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-03-01
Completion:: 2022-02-01

Conditions

Alzheimer Disease

Interventions

BIOLOGICAL

No Results Yet

NCT04226248 | COMPLETED | PHASE3

600 participants

CHIEF-PD (CHolinesterase Inhibitor to prEvent Falls in Parkinson's Disease)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-01-02
Completion:: 2024-05-02

Conditions

Parkinson Disease

Interventions

DRUG
OTHER

No Results Yet

NCT04187443 | RECRUITING | PHASE1

45 participants

MS-553 in Diabetic Retinopathy Patients With Central Involved Macular Edema

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-06-02
Completion:: 2026-10-30

Conditions

Diabetic Macular Edema
Macular Edema
Type 2 Diabetes With Diabetic Macular Edema
Type 1 Diabetes With Diabetic Macular Edema
Diabetic Retinopathy

Interventions

DRUG

No Results Yet

NCT04132414 | WITHDRAWN | NA

0 participants

Cerebral NIRS Monitoring During Anesthesia in Neonates and Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2022-12-31
Completion:: 2023-06-30

Conditions

Cerebral Oxygenation

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04130269 | RECRUITING

100 participants

Anxiety, Stress and Pain & Myocardial Infarction

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-29
Start Date:: 2020-04-07
Completion:: 2027-12-07

Conditions

Myocardial Infarction

Interventions

OTHER

No Results Yet

NCT04121806 | RECRUITING | NA

20 participants

Diet Intervention Treatment for Active Ulcerative Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-29
Start Date:: 2021-03-01
Completion:: 2026-09-30

Conditions

Colitis, Ulcerative

Interventions

OTHER

No Results Yet