Effects of Eggshell Membrane and Curcumin Extract Supplementation, Separately or Combined, on Recovery From Intense Exercise

Summary

Eggshell membrane and Curcumin supplementation prior to intense exercise may reduce inflammation, muscle and joint pain, and promote recovery. This proof-of-concept study will examine how ingestion of specially formulated versions of these nutrients affects recovery from intense exercise.

Conditions

• Exercise-induced Muscle Soreness
• Exercise-induced Joint Pain
• Exercise-induced Joint Stiffness
• Exercise-induced Cartilage Turnover

Interventions

DIETARY_SUPPLEMENT

NEM® brand eggshell membrane powder

500 mg/day of NEM® brand eggshell membrane powder in a single #0 capsule.

DIETARY_SUPPLEMENT

curQ+® brand highly absorbable curcumin

2,860 mg/day of curQ+® brand highly absorbable curcumin in a single 10 Oval softgel.

DIETARY_SUPPLEMENT

EM Placebo

500 mg/day of psyllium husk fiber powder in a single #0 capsule.

DIETARY_SUPPLEMENT

Curc Placebo

2,860 mg/day of coconut oil/polysorbate blend in a single 10 Oval softgel.

DIETARY_SUPPLEMENT

NEM® plus curQ+® combination

500 mg/day of NEM® brand eggshell membrane powder in a single #0 capsule PLUS 2,860 mg/day of curQ+® brand highly absorbable curcumin in a single 10 Oval softgel.

Sponsors & Collaborators

• Exercise & Sport Nutrition Lab, Texas A&M University

  collaborator UNKNOWN

• ESM Technologies, LLC

  lead INDUSTRY

Principal Investigators

• Richard B. Kreider, Ph.D. · Exercise & Sport Nutrition Lab, Texas A&M University

• Kevin J. Ruff, Ph.D. · ESM Technologies, LLC

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

40 Years

Sex

MALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2026-02-01

Primary Completion

2026-10-15

Completion

2026-12-31

Countries

• United States

Study Locations