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Effect of Collagen Supplementation on Tendinopathy

NCT04578418 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2024-11-04

No results posted yet for this study

Summary

Tendon injuries represent a significant problem in elite athletes. Therefore, prevention and effective treatment of tendon overload injury/tendinopathy is important. Among different treatment options, heavy-slow loading based rehabilitation is considered among the most efficient treatments in athletes. In this study, we will investigate if supplementation with hydrolyzed collagen in combination with a heavy-slow loading based 12 weeks rehabilitation regime can improve treatment of tendon overload injury/tendinopathy. The investigators will examine elite athletes with overload injury/tendinopathy with regards to symptoms (pain, function), tendon morphology (ultrasonography), and vascularization (Doppler US). The investigators hypothesize that collagen supplementation can have an improving effect on tendon pain and function. Thus, the investigation will show if a rehabilitation regime of collagen supplementation combined with heavy-slow mechanical loading can improve tendon healing compared to mechanical loading alone.

Conditions

  • Tendinopathy

Interventions

DIETARY_SUPPLEMENT

Hydrolyzed collagen

Hydrolyzed collagen supplementation twice daily

OTHER

Heavy slow resistance training

Heavy slow resistance training 3 times weekly

DIETARY_SUPPLEMENT

Placebo

Placebo supplementation twice daily

Sponsors & Collaborators

  • Team Denmark

    collaborator OTHER

  • University of Aarhus

    collaborator OTHER

  • Bispebjerg Hospital

    lead OTHER

Principal Investigators

  • Christian Couppé, PhD · Institute of Sports Medicine

  • Louis Lepetit Thomsen · Institute of Sports Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-09-16
Primary Completion
2025-01-01
Completion
2025-05-01

Countries

  • Denmark

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04578418 on ClinicalTrials.gov