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Long-term Effects of Avocado Consumption on Health in Pre-diabetic Individuals

NCT07752225 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2026-08-07

No results posted yet for this study

Summary

Primary aim of the study is to assess the effect of 12-week daily avocado consumption on cerebral blood flow and markers of cardio- and vascular health in both, the periphery and the brain, in pre-diabetic individuals with overweight or obesity. Secondary objective is to assess the effects of 12-week daily avocado consumption on brain insulin sensitivity after intranasal insulin delivery, vascular function, markers of metabolic health, cognition, and psychological well-being. For that purpose a total of 34 men and women between the ages of 40-75 years old, will participate in a randomised crossover intervention study.

Conditions

  • Prediabetes
  • Brain Insulin Sensitivity
  • Cerebral Blood Flow
  • Satiety and Food Intake
  • Food Reward
  • Brain Health
  • Vascular Function
  • Obesity & Overweight

Interventions

DIETARY_SUPPLEMENT

Avocados

Participants need to consume 1 avocado a day for 12 weeks.

Sponsors & Collaborators

  • Avocado Nutrition Center

    collaborator UNKNOWN

  • Maastricht University Medical Center

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
40 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-09-01
Primary Completion
2028-06-30
Completion
2028-08-31

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07752225 on ClinicalTrials.gov