Health for Hungary (H4H) - Longitudinal Collection of Blood Samples and Corresponding Data

Summary

The Health for Hungary (H4H) study collects blood samples and corresponding health data to investigate healthy aging and health-to-disease transitions in middle-aged and elderly participants.

Indications Studied:

Apparently healthy, symptom-free participants are enrolled and followed up to study the onset of new-onset diseases with special emphasis on non-communicable diseases (NCDs).

Study Design:

Single-country, multicenter, prospective, longitudinal survey.

Objectives:

The study aims to establish reference ranges of blood parameters using routine clinical blood tests and high-information-content methods, including proteomics, metabolomics and the so-called infrared molecular fingerprinting.

The study also aims to identify novel biomarkers of major non-communicable diseases, including atherosclerotic cardiovascular disease, cancer, diabetes and chronic respiratory disease.

Conditions

• Non-communicable Diseases (NCD)
• Neoplams
• Cancer
• Lung Cancer (NSCLC)
• Cardiovascular Diseases (CVD)
• Atherosclerotic Cardiovascular Disease (ASCVD)
• Peripheral Artery Disease (PAD)
• Coronary Artery Disease (CAD)
• Stroke (CVA) or TIA
• Diabetes Mellitus (DM)
• Type 2 Diabetes (T2DM)
• Prediabetes
• Chronic Respiratory Diseases
• Chronic Obstructive Pulmonary Disease (COPD)

Sponsors & Collaborators

• Szeged University

  collaborator OTHER

• Ludwig-Maximilians - University of Munich

  collaborator OTHER

• Max Planck Institute of Biochemistry

  collaborator UNKNOWN

• Technical University of Munich

  collaborator OTHER

• Helmholtz Zentrum München

  collaborator INDUSTRY

• Center for Molecular Fingerprinting Research Nonprofit LLC

  lead OTHER

Principal Investigators

• Ferenc Krausz, Prof, PhD · Center for Molecular Fingerprinting Research Nonprofit LLC

• Domokos Gerő, MD, PhD · Center for Molecular Fingerprinting Research Nonprofit LLC

Eligibility

Min Age

40 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2021-07-27

Primary Completion

2030-12-31

Completion

2030-12-31

Countries

• Hungary

Study Locations