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Optimized Diagnosis and Precision Medicine of MODY

NCT06111833 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1500

Last updated 2023-11-01

No results posted yet for this study

Summary

The goal of this observation is to establish a complete registry for the clinical manifestations, environment, genetic, and other related gene variation information of young-onset diabetic patients. Moreover, according to the physiological and pathological mechanisms of different genes, the impact on the clinical characteristics of diabetes, the therapeutic response to drugs, and the impact on complications will be analyzed.

The main questions are:

1. The distribution of different types of MODY
2. The phenotypes and clinical characteristics of different types of MODY
3. Response to antidiabetic drugs among different types of MODY

Once the participant is enrolled, their questionnaire information (including disease course and development, health history, family history, drug history, etc.), medication, outpatient/inpatient medical history, etc. will be collected and logged in. Blood and urine samples will also be collected for biochemical tests genetic testing, etc.

At the same time, the investigators will conduct a continuous follow-up on a regular basis (3 months, 6 months, 12 months, 24 months, and 5 years after the study subject is enrolled).

Young-onset type 2 diabetes will be compared to see the difference in clinical presentations and responses to antidiabetic drugs.

Conditions

  • Maturity-Onset Diabetes of the Young (MODY)
  • Type 2 Diabetes
  • Diabetes Complications

Sponsors & Collaborators

  • National Health Research Institutes, Taiwan

    collaborator OTHER

  • Taichung Veterans General Hospital

    lead OTHER

Principal Investigators

  • Yi-Jing Sheen, MD. PHD · Division of Endocrinology and Metabolism in Taichung Veterans General Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-22
Primary Completion
2028-04-21
Completion
2028-05-21

Countries

  • Taiwan

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06111833 on ClinicalTrials.gov