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Metabolic Control of Aging and Disease - the MetAGE Deep Phenotyping Cohort

NCT06511297 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 650

Last updated 2026-02-17

No results posted yet for this study

Summary

The goal of this prospective observational study is to identify and validate blood based aging biomarkers in relation to cardiometabolic phenotypes of young and old, female and male subjects with or without obesity.

The main question is to gain insights into the interaction of obesity related metabolic alteration and aging, and the relevance of loss of metabolic control in the development of age-related diseases in order to build a foundation for targeted drug- and lifestyle interventions in future studies.

Conditions

  • Obesity
  • Aging
  • Aging Problems
  • Metabolic Syndrome

Interventions

DIAGNOSTIC_TEST

comprehensive metabolic phenotyping

The investigators will employ state of the art techniques to metabolically phenotype the study groups using brain, cardiac and whole body magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), wearables, optical coherence tomography longitudinally. In addition, a battery of patient reported outcome measures will be used to explore psychosocial aspects of aging.

Sponsors & Collaborators

  • Medical University of Graz

    collaborator OTHER

  • University of Graz

    collaborator OTHER

  • Thomas Scherer

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-05-05
Primary Completion
2035-01-01
Completion
2036-01-01

Countries

  • Austria

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06511297 on ClinicalTrials.gov