Effects of Blood Gas Perturbations
NCT07701603 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2026-07-14
Summary
In this study, the effects of blood gas perturbations on neuromuscular function of the diaphragm and lower limbs at rest and during exercise will be investigated.
Conditions
- Healthy
Interventions
- OTHER
-
Gas perturbation
Participants will be breathing a gas mixture of either room air, or hypoxia, or hypercapnia, or a combination of both during 2h. This is followed by an all-out breathing exercise test against a small resistance, while still being in the respective gas condition.
Sponsors & Collaborators
-
Swiss Federal Institute of Technology
lead OTHER
Principal Investigators
-
Spengler M. Christina, Prof. · Exercise Physiology Lab, Department of Health Sciences and Technology
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-08-31
- Primary Completion
- 2029-12-31
- Completion
- 2029-12-31
More Related Trials
-
The Effects of Strength Training Volume, Intensity, and Breathing Techniques on Intraocular Pressure and Retinal Blood Vessels
NCT07326462 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Modulation of Metabolic Rate by Inorganic Nitrate
NCT02022176 ·Status: COMPLETED ·Phase: NA
-
Effect of Chlorogenic Acids on the Human Vasculature
NCT03520452 ·Status: COMPLETED ·Phase: NA
-
Influence of Bedrest and Hypocaloric Nutrition on Endothelium-Dependent Vasoreactivity
NCT00175968 ·Status: COMPLETED ·Phase: PHASE1
-
Measurement of Retinal Venous Pressure Under Short-term Low-oxygen Environment
NCT01771757 ·Status: COMPLETED
-
Effect of Changing Physiological Conditions on Myogenic Oscillations: Pilot Study
NCT03719001 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Effect of Glucose on Ocular Blood Flow
NCT00350129 ·Status: COMPLETED
-
Pharmacological Intervention in Insulin Resistance Targeting Autonomic Nerve Activity
NCT00689208 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults
NCT03738943 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Study of the Response of Human Small Blood Vessels
NCT00001622 ·Status: COMPLETED ·Phase: PHASE1
-
Physiological Assessment of the Endothelium - Circadian Rhythm and Role of the Sympathetic Nervous System
NCT01713374 ·Status: COMPLETED ·Phase: NA
-
Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers
NCT00152724 ·Status: COMPLETED
-
Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans
NCT04769206 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Autonomic Nervous System and Nitric Oxide Interactions
NCT01137253 ·Status: COMPLETED ·Phase: PHASE1
-
The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood Flow
NCT04777383 ·Status: TERMINATED ·Phase: NA
-
Effect of Raised End-Tidal pCo2 on Choroidal Volume
NCT06275308 ·Status: RECRUITING ·Phase: NA
-
Nitric Oxide to Improve Blood Flow in Sickle Cell Disease
NCT00009581 ·Status: COMPLETED ·Phase: PHASE2
-
Peripheral Chemoreflex/Arterial Baroreflex Interaction in Patients With Electrical Carotid Sinus Stimulation
NCT02587533 ·Status: COMPLETED ·Phase: NA
-
Effect of Systemic Cooling in Vasospasms
NCT00409123 ·Status: COMPLETED
-
Effects of Neupro on Cardiovascular Observations in Patients With Restless Legs Syndrome
NCT01455012 ·Status: COMPLETED ·Phase: PHASE4
-
Dose and Response of Dietary Nitrate in Healthy and Active Men
NCT01961427 ·Status: COMPLETED ·Phase: NA
-
The Role of S-nitrosohemoglobin in Regulating Systemic Blood Flow During Hypoxia and Normoxia
NCT01905696 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Vascular Function Improvements After Chronic Passive Stretching
NCT04271241 ·Status: COMPLETED ·Phase: NA
-
Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Environmental Stress
NCT01830335 ·Status: COMPLETED ·Phase: PHASE4
-
Nitric Oxide Consumption as a Predictor of Vasospasm in Subarachnoid Hemorrhage
NCT07614906 ·Status: RECRUITING