Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers
NCT00152724 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 85
Last updated 2017-11-01
Summary
Microvascular dysfunctions are critical events in several diseases including diabetes. This study will develop a methodology for microvascular investigation in human skin. The purpose of the study is to investigate the physiological response of the cutaneous microcirculation to physical, thermal, mechanical or chemical stimulations.
Conditions
- Healthy Volunteers
Interventions
- DEVICE
-
pressure strain system, iontophoresis
- DRUG
-
scopolamin
- DRUG
-
emla
- DRUG
-
capsaicin
- DRUG
- DRUG
-
clopidogrel
- DRUG
-
celecoxib
- DRUG
-
indomethacin
- DRUG
-
acetylcholine
- DRUG
-
sodium nitroprusside
- DRUG
-
brethyllium
- DEVICE
-
general and local heating
Sponsors & Collaborators
-
University Hospital, Angers
lead OTHER_GOV
Principal Investigators
-
Jean Louis SAUMET, MD - PhD · University Hospital, Angers
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 1996-01-31
- Primary Completion
- 2008-11-30
- Completion
- 2008-11-30
Countries
- France
Study Locations
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